Major drop in antibiotics for food animals in U.S.

fluoroquinolone antibiotics, however, increased by 24 percent.

Public health and animal medicine consultant Gail Hansen said the reductions don’t surprise her, given that 2017 was the first year that medically important antibiotics weren’t allowed to be sold for growth promotion or feed efficiency.

“Overall, this is good news on the antibiotic stewardship front,” Hansen told CIDRAP News. “It shows the FDA guidance was successful in reducing the amount of antibiotics sold, without an increase in animal health or food safety problems during that time.”

Among the food-animal groups, the largest decline in antibiotic sales was seen in chickens. The 47 percent decrease from 2016 to 2017 is likely linked to the poultry industry’s consumer-driven shift to raising chicken without medically important antibiotics. But sales of medically important antibiotics also dropped by 35 percent in cows, 35 percent pork in pigs, and 11 percent in turkeys.

Overall, medically important antibiotics account for 51 percent of the antibiotics sold for use on food animals. The other 49 percent are antibiotics that aren’t used in human medicine.

Concerns about high antibiotic use in pigs, cows
Still, the Natural Resources Defense Council (NRDC), which is among a number of groups that have advocated for restrictions on the use of medically important antibiotics in food-animal production, points out that the beef and pork industries remain high users of these drugs, accounting for 2.3 million and 2.0 million kg in sales in 2017, respectively, compared with 268,000 kg in poultry. One of the concerns of these groups is the continued use of medically important antibiotics in healthy animals to prevent disease. 

“We are seeing real progress, but the American meat industry continues to have a drug problem and the clock is ticking to solve it,” NRDC senior attorney Avinash Kar said in a press release. “Far more antibiotics important to humans still go to cows and pigs—usually when they’re not sick—than to people, putting the health of every single one of us in jeopardy.”

While the FDA still allows antibiotics to be used to prevent disease in livestock, the World Health Organization has called for an end to the practice, citing concern that it contributes to antimicrobial resistance. In October, the European Parliament voted to limit use of preventive antibiotics to individual animals, and only when a veterinarian believes there is a high risk of infection. That legislation won’t become law until 2022.

Matthew Wellington, antibiotics program director for the US PIRG (Public Interest Research Group) Education Fund, said that while the report is good news, he’d like to see the FDA take more steps to reduce antibiotic use in food-producing animals.

“The FDA should implement ambitious reduction targets for antibiotic use in the meat industry, and ensure that these medicines are used to treat sick animals or control a verified disease outbreak, not for routine disease prevention,” Wellington said in a statement.

The FDA has not indicated that it plans to set reduction targets for antibiotic use in animal agriculture, as has been done in the United Kingdom and in several European countries, but Gottlieb noted that the agency’s Center for Veterinary Medicine (CVM) is planning further action. In a 5-year action plan released in September, the CVM said it will bring the remaining 5 percent of medically important antibiotics used in livestock under veterinary supervision; improve data on antibiotic sales, use, and resistance in food animals; and encourage the development of alternative therapies for sick animals.

“While I’m very pleased with the results of the report, and the efforts by all of our stakeholders thus far to improve antimicrobial stewardship, our work isn’t yet done when it comes to fighting antimicrobial resistance,” Gottlieb said.