• The Data Is in — Stop the Panic and End the Total Isolation

    “Leaders must examine accumulated data to see what has actually happened rather than keep emphasizing hypothetical projections,” Dr. Scott W. Atlas writes. The policymakers should “combine that empirical evidence with fundamental principles of biology established for decades; and then thoughtfully restore the country to function.” He say that the appropriate policy, based on fundamental biology and the evidence already in hand, is to institute a more focused strategy like some outlined in the first place: Strictly protect the known vulnerable, self-isolate the mildly sick and open most workplaces and small businesses with some prudent large-group precautions.

  • COVID-19 and America’s Counter-Terrorism Response

    Since the Sept. 11 attacks, U.S. foreign policy, national security, and law enforcement have been dominated by counter-terrorism considerations, even while a number of counter-terrorism experts have cautioned against overemphasizing the terrorist threat. Lydia Khalil writes that, at the same time, for various reasons, U.S. law enforcement has found it more challenging to deal with the more serious threat of terrorism the United States is facing – far-right domestic terrorism – a threat which now eclipses the threat posed by foreign Islamist jihadists, and which is only going to grow. If anything could ever shake the United States out of its counter-terrorism fixation it would be a crisis of even greater magnitude than 9/11. It seemed like that moment finally came with the COVID-19 pandemic, “[y]et what we have seen so far is the opposite. Instead of reorienting toward other paradigms and reexamining its strategic priorities, the United States continues to reflexively overextend its counter-terrorism tools to deal with some of the more problematic aspects of the virus’ spread,” she writes.

  • Oxford Scientists Take Early Lead in Race to Create Vaccine

    Scientists at Oxford University are racing to develop a vaccine for the coronavirus well ahead of the standard medical timeline. VOA News reports that the scientists have expressed confidence in their ability to do it quickly, raising hopes around the world that a vaccine will not have to wait until next year. The first injections of the vaccine being developed by the university’s Jenner Institute in Britain took place last week. Scientists are planning to massively scale up their testing in a little over a month, a time frame that is currently faster than other vaccine development efforts. The New York Times reported Monday that the scientists plan to test their vaccine on more than 6,000 people by the end of May. 

  • DNA May Hold the Key to Protecting Populations from COVID-19

    Scientists from The University of Western Australia’s Faculty of Science are part of a global team that is developing a new DNA test for COVID-19, which can provide faster and more detailed results than other tests. UWA says that this test can be used to understand how COVID-19 is mutating, aid vaccine development and understand its journey across populations globally – for instance, how it adapts to a new host. It is currently being used for COVID-19 research, but once approved by the US Food and Drug administration it can be used for both the diagnostic testing of patients and to enable a better understanding of the virus. The test is based on technology developed through the DNA Zoo project, a global initiative that analyses DNA from different species to help researchers, leaders and policy-makers better understand species through their DNA as well as threats to their survival.

  • NERVe: A “Stopgap” Ventilator Developed for COVID-19 Use during Medical Supply Shortage

    While hospitals across the U.S. faced a possible shortage of mechanical ventilators due to COVID-19, a self-assembled “skunk works” team at Lawrence Livermore National Laboratory (LLNL) worked tirelessly to prototype a simple ventilator design for quick and easy assembly from available parts. Lawrence Livermore National Laboratory says that the design, dubbed the “Novel Emergency Response Ventilator” (NERVe), is derived from proven concepts and contains parts that are not being used by commercial ventilator manufacturers, to avoid disrupting already thin supply chains. It is designed to meet the functional requirements of COVID-19 patients requiring mechanical ventilation, including a simple user interface, air flow circuits for inhalation and exhalation, and alarms to notify physicians if air pressures get too low. It can operate in a continuous ventilation mode — common for late-stage COVID-19 patients — but can adapt to patients who spontaneously breathe on their own.

  • Antibodies from Llamas Could Help in Fight against COVID-19

    The hunt for an effective treatment for COVID-19 has led one team of researchers to find an improbable ally for their work: a llama named Winter. The team — from The University of Texas at Austin, the National Institutes of Health and Ghent University in Belgium — reports their findings about a potential avenue for a coronavirus treatment involving llamas on May 5 in the journal Cell. The paper is currently available online as a “pre-proof,” meaning it is peer-reviewed but undergoing final formatting. UT News reports that the researchers linked two copies of a special kind of antibody produced by llamas to create a new antibody that binds tightly to a key protein on the coronavirus that causes COVID-19. This protein, called the spike protein, allows the virus to break into host cells. Initial tests indicate that the antibody blocks viruses that display this spike protein from infecting cells in culture.

  • Federal COVID-19 Physical Distancing Measures Expire, More States Reopen

    Today the White House’s national physical (social) distancing guidelines—”15 days and 30 days to slow the spread”—expired, leaving the opening of states now in the hands of governors who are attempting to balance public health guidelines, the realities of testing, and mounting economic pressure to reopen communities. The U.S. now has 1,057,800 COVID-19 cases, and 61,700 deaths.

  • Life after Lockdowns

    In many things 90 percent is just fine; in an economy it is miserable. The 90 percent economy. It is better than a severe lockdown, but it is far from normal. The missing bits include large chunks of everyday life. Rides on the metro and on domestic flights are down by a third. Discretionary consumer spending, on such things as restaurants, has fallen by 40 percent and hotel stays are a third of normal. People are weighed down by financial hardship and the fear of a second wave of covid-19. Bankruptcies are rising and unemployment, one broker has said, is three times the official level, at around 20 percent. The Economist writes that if the post-lockdown rich world suffers its own brand of the 90 percent economy, life will be hard—at least until a vaccine or a treatment is found. A plunge in GDP in America of anything like 10 percent would be the largest since the second world war. The more suffering COVID-19 causes, the more profound and enduring its economic, social and political effects are likely to be. “How lockdowns ease will itself affect the scale of economic damage,” the Economist notes. “For instance, the cost-benefit calculus points towards opening schools first (see article). But, however sensibly restrictions are eased, powerful forces will hold economies back.”

  • Coronavirus “Not Man-Made”: U.S. Intelligence Community

    The U.S. intelligence community, in a rare public statement on Thursday, said that evidence shows that the virus was not engineered in a Chinese laboratory. The U.S. intelligence community “concurs with the wide scientific consensus that the COVID-19 virus was not man-made or genetically modified,” the Office of the Director of National Intelligence said. Talk that the COVID-19 virus was created in a Chinese lab, or escaped from a lab, has persisted for weeks, as have other theories, many of which have been discredited as conspiracy theories or as part of disinformation campaigns.

  • The COVIDSafe App Was Just One Contact Tracing Option. These Alternatives Guarantee More Privacy

    Since its release on Sunday, experts and members of the public alike have raised privacy concerns with the Australian federal government’s COVIDSafe mobile app. Many Australians have said that they worried about “the security of personal information collected” by the app. In its coronavirus response, the government has a golden opportunity to build public trust. There are other ways to build a digital contact tracing system, some of which would arguably raise fewer doubts about data security than the app.

  • Controlling an Influenza Outbreak without a Specific Vaccine

    A group of pandemic modelling experts have published new research that simulated viral influenza outbreaks to examine the efficacy of pandemic interventions in the absence of a tailored vaccine. The general use of low-efficacy vaccines, coupled with a targeted application of antiviral medications, may be effective at countering the spread of influenza pandemics, new research has found.

  • Millions of U.S. Workers at Risk of Infections on the Job, Researchers Calculate, Emphasizing Need to Protect Against COVID-19

    A University of Washington researcher calculates that 14.4 million workers face exposure to infection once a week and 26.7 million at least once a month in the workplace, pointing to an important population needing protection as the novel coronavirus disease, COVID-19, continues to break out across the U.S. Jake Ellison writes for UW News that Marissa Baker, an assistant professor in the UW School of Public Health, based her calculations on research she published in 2018 in the American Journal of Industrial Medicine. In that paper, Baker and co-authors calculated that about 8 percent of workers in Federal Region X — comprised of Alaska, Washington, Oregon and Idaho — work in jobs where exposure to infection or disease occurs at least once a week at work. Those risks include flu-like illnesses, MRSA and other respiratory illnesses, like COVID-19, as well as wound infections.

  • U.S. Hits 1 Million COVID-19 Cases as States Take on Testing

    The U.S. case count for COVID-19 topped 1 million cases yesterday, meaning the country has accounts for a third of all reported cases of the novel coronavirus in the world. In total, the United States now has 1,002,498 cases, including 57,533 fatalities. The milestone comes a day after the world surpassed 3 million cases in the 4 months since the virus was first detected in Wuhan, China. Less than 1 month ago—on 2 April—the global total hit 1 million cases.

  • Virologists Show that Sample Pooling Can Massively Increase Coronavirus Testing Capacity

    A new procedure will help to meet the high demand for testing in mass coronavirus screening programs needed in the early identification and isolation of asymptomatic individuals. The pooling of samples before testing is a safe and well-established procedure in blood banking. The team from the Institute of Virology has adapted and tested this method for use in coronavirus diagnostics. Saarland University says that samples from several individuals are pooled and tested together in a single tube using sensitive molecular biological detection methods. Only if the pool result is positive do the samples need to be tested individually. When the infection rate is low and only a few people are infected, pool testing can significantly expand the testing capacity of the existing laboratory infrastructure. The team has been using the new procedure at Saarland University Hospital in Homburg since mid-March to protect vulnerable patients from infection by asymptomatic SARS-CoV-2 carriers. The success of the pool testing procedure has now led to its use in screening residents and staff at nursing and residential care homes in Saarland.

  • Oxford COVID-19 Vaccine Begins Human Trial Stage

    University of Oxford researchers have begun testing a COVID-19 vaccine in human volunteers in Oxford. Around 1,110 people will take part in the trial, half receiving the vaccine and the other half (the control group) receiving a widely available meningitis vaccine. Of the first two volunteers to take part today, one will likewise receive the vaccine and the other the control. Oxford says that the researchers started screening healthy volunteers (aged 18-55) in March for their upcoming ChAdOx1 nCoV-19 vaccine trial in the Thames Valley Region. The vaccine is based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein, and has been produced in Oxford.