• Synthetic virus tackles antimicrobial resistance

    Antibiotic resistance has become an ever-growing global challenge, with more than 700,000 people across the world dying from drug resistant infections every year. As a result, antibiotic discovery has fallen well behind its historical rate, with traditional discovery methods being exhausted. Scientists have engineered a brand new artificial virus that kills bacteria on first contact. This new virus is built using the same geometric principles that determine structures of naturally occurring viruses, known as polyhedral capsids.

  • Making production of high explosives cheaper, safer

    Scientists from the U.S. Army Research Laboratory (ARL) and the Lawrence Livermore National Laboratory found a solution to a significant challenge in making high-energy explosives. They safely improved the overall chemical yield derived from diaminoglyoxime, known as DAG, and significantly increased the amount of material made per reaction.

  • Unless carbon emissions are reversed, global temperature targets will be missed soon

    New scientific projections could be the catalyst the world has sought to determine how best to meet its obligations to reduce carbon emissions and better manage global warming as defined by the Paris Agreement. A new study projects that if immediate action isn’t taken, the earth’s global average temperature is likely to rise to 1.5°C above the period before the industrial revolution within the next 17-18 years, and to 2.0°C in 35-41 years respectively if the carbon emission rate remains at its present-day value.

  • Step-by-step horsepox study intensifies dual-use research debate

    The publication last week of a research paper offering a manual for re-creating an orthopoxvirus has been harshly criticized by both scientists and biosecurity experts as reckless and dangerous. The research demonstrates the potential to recreate the virus that causes smallpox—one of the greatest scourges the world has ever faced and eradicated. “The risks posed by the publication of methods that could ease the pathway for synthesizing smallpox should have been carefully weighed from the outset,” says one expert. Analysts say that the publication further accentuates the need for urgent global dialogue to develop clear norms and actions for reducing biological risks posed by advances in technology. “As governmental oversight continues to lag behind biotechnology breakthroughs, academic and private stakeholders conducting, funding, and publishing research - as well as those developing new technologies – also must take responsibility for mitigating risk,” says the expert.

  • The synthesis of horsepox virus and the failure of dual-use research oversight

    On 19 January 2018, the open access scientific journal PLOS One published an article that describes the de novo synthesis of horsepox virus, the first ever synthesis of a member of the orthopoxvirus family of viruses that includes the variola virus that causes smallpox. This research crosses a red line in the field of biosecurity. Given the high degree of homology between orthopoxviruses, the techniques described in this article are directly applicable to the recreation of variola virus. The synthesis of horsepox virus takes the world one step closer to the reemergence of smallpox as a threat to global health security. The reemergence of smallpox would be a global health disaster. Prior to its eradication, smallpox killed an estimated 300 million people, more people than all the wars of the twentieth century combined. Based on these considerations, the horsepox synthesis research is all risk and no reward. Given the known risks of this research for pioneering a technique that can be used to recreate variola virus and its questionable benefits, the publication of this article represents a failure of PLOS One to exercise its responsibility to carefully consider the biosecurity implications of the research it publishes.

  • Administration waives more than 30 environmental laws for New Mexico section of border wall

    The Trump administration on Monday waived more than thirty environmental laws to speed construction of twenty miles of border wall in eastern New Mexico, the third time the waiver has been used by the Trump administration. The waiver is meant to allow construction of the New Mexico border wall section without having to comply with laws that protect clean air, clean water, public lands, or endangered wildlife.

  • Blast, impact simulations help researchers better understand injuries and body armor

    Researchers at Sandia Lab have studied the mechanisms behind traumatic brain injury for about a decade. Their traumatic injury modeling and simulation project began with a head-and-neck representation, and now they’ve created a high-fidelity, digital model of a man from the waist up to study the minute mechanisms behind trauma. The specialized computer modeling and simulation methods help researchers better understand how blasts on a battlefield could lead to traumatic brain injury and injuries to vital organs, like the heart and lungs.

  • Drones learn to navigate autonomously by imitating cars, bicycles

    Researchers have developed an algorithm called DroNet which allows drones to fly completely by themselves through the streets of a city and in indoor environments. The algorithm had to learn traffic rules and adapt training examples from cyclists and car drivers.

  • Discrepancies between satellite and global model estimates of land water storage

    Researchers have found that calculations of water storage in many river basins from commonly used global computer models differ markedly from independent storage estimates from GRACE satellites. The findings raise questions about global models that have been used in recent years to help assess water resources and potentially influence management decisions.

  • Climate engineering, if started, would have severe consequences if stopped abruptly

    Facing a climate crisis, we may someday spray sulfur dioxide into the upper atmosphere to form a cloud that cools the Earth, but suddenly stopping the spraying would have a severe global impact on animals and plants, according to the first study on the potential biological impacts of geoengineering, or climate intervention. “Rapid warming after stopping geoengineering would be a huge threat to the natural environment and biodiversity,” says one expert. “If geoengineering ever stopped abruptly, it would be devastating, so you would have to be sure that it could be stopped gradually, and it is easy to think of scenarios that would prevent that. Imagine large droughts or floods around the world that could be blamed on geoengineering, and demands that it stop. Can we ever risk that?”

  • Climate change will displace millions in coming decades. Nations should prepare now to help them

    By the middle of this century, experts estimate that climate change is likely to displace between 150 and 300 million people. If this group formed a country, it would be the fourth-largest in the world, with a population nearly as large as that of the United States. Yet neither individual countries nor the global community are completely prepared to support a whole new class of “climate migrants.” The scale of this challenge is unlike anything humanity has ever faced. By midcentury, climate change is likely to uproot far more people than the Second World War, which displaced some 60 million across Europe, or the Partition of India, which affected approximately 15 million. The migration crisis that has gripped Europe since 2015 has involved something over one million refugees and migrants. It is daunting to envision much larger flows of people, but that is why the global community should start doing so now.

  • Climate change will displace millions of people. Where will they go?

    The 1951 Refugee Convention defines a protected refugee as someone who leaves his or her home country due to racial, religious, or social persecution, or reasonable fear of such persecution. These refugees have the right to seek asylum and protection from participating members of the United Nations (though these countries are not obligated to take them in). However, people displaced by climate change do not fit this definition. At the international level, there is no legal mechanism in place to protect climate migrants’ rights and to ensure assistance from other countries. For climate relocation to work, governments need to care and commit to international responsibility and burden-sharing. However, in the current global political context of fear of terrorism, an increased refugee influx into Europe, and an overall rise of xenophobia, countries are more likely to opt for stricter policies on cross-border migration.

  • Using fungi for self-healing concrete to fix bridges

    America’s crumbling infrastructure has been a topic of ongoing discussion in political debates and campaign rallies. The problem of aging bridges and increasingly dangerous roads is one that has been well documented and there seems to be a consensus from both democrats and republicans that something must be done. Researchers propose using fungi for self-healing concrete — a low-cost, pollution-free, and sustainable approach to shoring up U.S. infrastructure.

  • Thorium reactors could dispose of large amounts of weapons-grade plutonium

    Scientists are developing a technology enabling the construction of high-temperature, gas-cool, low-power reactors with thorium fuel. The scientists propose to burn weapons-grade plutonium in these units, converting it into power and thermal energy. Thermal energy generated at thorium reactors may be used in hydrogen industrial production. The technology also makes it possible to desalinate water. 

  • Checking chemical detectors’ sensitivity to chemicals

    The Joint Chemical Agent Detector (JCAD) has become an important defense tool on battlefields and in war-torn cities over the last few years. About the size and shape of a VHS tape or a hardcover bestselling novel, JCADs sound an alarm and begin to light up if nerve agents such as sarin or blister agents such as mustard gas are present. The detectors are already designed to withstand intense environments and repeated use. But when the Department of Defense wanted a way to check the devices’ sensitivity to chemicals over time, a measurement team at the National Institute of Standards and Technology (NIST) was called in to provide a cost-effective solution.