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How Antibodies from Llamas May Lead to COVID-19 Treatment
Scientists hope the special antibodies that llamas make can be directed against SARS-CoV-2 to help find our way out of the pandemic. Rockefeller University says that humans, too, make antibodies against SARS-CoV-2, and many groups are working on developing treatments based on them. Llama antibodies, however, come in a simpler design than their human counterparts. “For reasons that we don’t really understand, these animals make this variant of antibody that just has fantastic properties,” says Michael P. Rout, a structural biologist at Rockefeller. “It contains the good disease-recognizing parts of a human antibody, packed into a condensed warhead.”
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Face Masks Could Be a Better Defense against COVID-19 than Hand Washing
Face masks could provide a better defense against Covid-19 than hand washing or social distancing, according to a study of a coronavirus outbreak on board a navy ship. Patrick Sawyer writes in The Telegraphthat experts say the study strengthens the argument for masks to be made compulsory for people in indoor settings such as shops, restaurants and offices.
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U.K. to See Three Waves of Unemployment as a Result of COVID-19, Experts Warn
The UK will be hit with three waves of unemployment as a result of the Coronavirus crisis, experts have claimed as official data is on Tuesday expected to show a record monthly rise in joblessness. Anna Mikhailova writes in The Telegraph that new figures from the Office for National Statistics (ONS) will reflect the first wave of jobs lost since the lockdown began. Analysis by the Resolution Foundation, the economic think tank, predicts the April data will show a record monthly rise of people out of work, up from the latest figure of 1.29m in March.
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This Disastrous Lockdown Can Never Be Repeated, Even If the Virus Returns
Three months after we entered lockdown, as we tiptoe out to non-essential stores and meet a lonely relative, we can begin to benefit from something previously unavailable – experience. William Hague writes in The Telegraph that instead of having to rely entirely on widely varying mathematical models and fight an unknown virus in a fog of uncertainty, governments can start to see what has actually worked in different places around the world. The most important thing we now know is the true cost of a national lockdown, not just in economic but in human terms. The lockdown was a disaster on many fronts. “Such a disaster cannot under any circumstances be repeated. There can be no second lockdown.”
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If Scientists Are Wrong about COVID, They Must Be Held to Account
The world has panicked, and the British government has panicked worse than most. We scared ourselves and our fellow citizens out of rational thought. Matthew Parris writes in The Times that by losing our sense of proportion I submit we have crashed our economy, crashed our education system, our performing arts, our tourist and travel industry, and blighted the life chances of a whole generation. Before too long, commentators, politicians and scientists may be blushing at the mess we made of our national response to the coronavirus pandemic. Commentators will duck. Politicians will be blamed for everything, and who can doubt that political leadership has been a shambles? But how about “the science”, those men and women, academics, doctors and mathematical modelers, in whose expertise ministers once placed their trust?
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Was the Coronavirus Outbreak an Intelligence Failure?
As the coronavirus pandemic continues to unfold, it’s clear that having better information sooner, and acting more quickly on what was known, could have slowed the spread of the outbreak and saved more people’s lives. Initial indications are that the U.S. intelligence community did well in reporting on the virus once news of the outbreak in China became widely known by early January. Whether it could have done more before that time, and why the Trump administration did not act more decisively early on, will have to wait for a future national coronavirus commission to help us sort out.
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COVID-19 Activity Escalating in Africa, Middle East
Though Latin America has evolved as the world’s biggest hot spot, COVID-19 activity is escalating in other regions, including Africa, which just passed 200,000 cases, and the Middle East, where cases have accelerated over the past 3 weeks. The global today rose to 7,440,350 cases, and 418,563 people have died from their infections.
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COVID-19's “Devastating” Impact on Cancer Services
COVID-19 has “wreaked havoc” on cancer services, experts have said, as new data reveals referrals fell to their lowest ever levels in the first full month of lockdown. Henry Bodkin writes in The Telegraph that NHS figures show that numbers more than halved between March and April. The statistics also revealed that the proportion of patients seen by a cancer specialist within two weeks after an urgent GP referral is at its lowest level since records began.
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Exploring the Links Between Coronavirus and Vitamin D
In the past decade, studies have found that taking vitamin D can lower the odds of developing respiratory infections like the cold and the flu, especially among people who have documented deficiencies. Anahad O’Connor writes in the New York Times that now scientists are trying to find out whether vitamin D might also help protect against Covid-19.
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Facemasks Shown to Cut Spread of Coronavirus
The mandatory use of facemasks slows the growth in new cases of COVID-19 by 40 percent, according to a German study that provides the best evidence yet for their use. Tom Whipple writes in The Times that the research was able to use the staggered introduction of masks in shops and public transport across Germany as a natural experiment to test how effective they were. By looking at new cases in the days that followed, the researchers concluded that there is “strong and convincing statistical support” that the masks “strongly reduced the number of incidences.”
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Why Some Nursing Homes Are Better than Others at Protecting Residents and Staff from COVID-19
The coronavirus pandemic has posed a serious threat to the U.S. long-term care industry. A third of all deaths have been nursing home residents or workers – in some states it’s more than half. Anna Amirkhanyan, Austin McCrea, and Kenneth J Meier write in The Conversation that, yet, some long-term care facilities have managed to keep the virus at bay. For example, veterans’ homes in California have seen only a handful of cases among roughly 2,100 residents. And preliminary results of our research on COVID-19 cases and deaths in nursing homes also support the idea that some homes are doing better than others at protecting clients and staff from COVID-19. Why might this be?
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States Are Making It Harder to Sue Nursing Homes over COVID-19, and that Immunity from Lawsuits Is a Bad Idea
The coronavirus has devastated nursing homes across the country, killing tens of thousands of vulnerable older Americans. Nursing homes did not cause the pandemic, but poor infection control, inadequate staffing and sluggish mitigation allowed the virus to spread. Tara Sklar and Nicolas Paul Terry write in The Conversation that rather than doing more to hold these facilities accountable, however, states increasingly are protecting them from lawsuits. That shift is happening quickly. At least 21 states have taken actions within the last four months to limit the liability of health care providers, with nine states expressly including nursing homes. The industry is calling for similar protection in other states, and at the federal level, nursing homes are connecting with other trade groups to push for expansive, national immunity from lawsuits. Essentially, these states are protecting nursing homes from aggrieved residents and their loved ones who may have suffered harm, injuries or death due to their actions – or inactions – during COVID-19.
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Could Pressure for COVID-19 Drugs Lead the FDA to Lower Its Standards?
Given the death, suffering, social disruption and economic devastation caused by COVID-19, there is an urgent need to quickly develop therapies to treat this disease and prevent the spread of the virus. But the Food and Drug Administration, charged with the task of evaluating and deciding whether to approve new drugs and other products, has a problem. Leigh Turner writes in The Conversation that the FDA’s standards appear to be dropping at a time when rigorous regulatory review and robust oversight are crucial. For example, on March 28, the FDA granted emergency use authorization (EUA) for chloroquine phosphate and hydroxychloroquine sulfate, despite the drugs having known safety concerns and negligible evidence of efficacy in treating COVID-19. As a specialist in bioethics and public health, I see troubling signs that suggest the FDA’s new program for expediting reviews of potential therapies for COVID-19 is not working as it should. Instead, its regulatory oversight has been weakened. In its place, I see signs of political interference, inappropriate pressure to authorize products for emergency use, and an overwhelming surge of clinical studies that challenges the FDA’s capacity to carefully scrutinize them before deciding whether they should proceed.
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Prof Karol Sikora: COVID-19 Death Toll May Be Less than Half of What Has Been Recorded
The Covid-19 death toll may be less than half of what has been recorded because many victims of the pandemic would have died soon anyway, one of Britain’s leading medics has said. Jack Hardy writes in The Telegraph that Professor Karol Sikora, a senior oncologist who has built a huge Twitter following for his positive takes on the virus crisis, said doctors were sometimes too eager to put Covid-19 on death certificates.
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Coronavirus: Five Reasons Why the U.K. Death Toll Is So High
At the start of the coronavirus pandemic, UK government advisers suggested that 20,000 UK deaths would be a good outcome. Today, the tally sits at more than 45,000. Jasmina Panovska-Griffiths writes in The Conversation that there is no doubt the UK has been hit hard by coronavirus, and has the second-largest number of deaths worldwide, trailing only the USA which has five times the population and 111,139 deaths. Where did the UK go wrong? And how will it prevent further deaths if a secondary pandemic wave occurs as it reopens? Modelling and epidemiology give us some clues.
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