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New gene therapy approach offers better treatment of botulism exposure, other illnesses
The current method to treat acute toxin poisoning is to inject antibodies, commonly produced in animals, to neutralize the toxin. This method, however, has challenges ranging from safety to difficulties in developing, producing and maintaining the anti-serums in large quantities. New research shows that gene therapy may offer significant advantages in prevention and treatment of botulism exposure over current methods, and may have applicability to other illnesses.
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New device improves radiation detection
In a move that could have important implications for national security, researchers have created a very sensitive and tiny detector that is capable of detecting radiation from various sources at room temperature. The detector is eight to nine orders of magnitude —100 million to as high as 1 billion — times faster than the existing technology. The researchers sought to utilize the exceptional electronic carrier properties of graphene to create the photo detector device. Graphene is made of carbon atoms that are arranged in a honeycomb-like geometrical structure (the diameter of a human hair is 300,000 times thicker than a two-dimensional sheet of graphene).
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Ricin toxin vaccine shows promise in a non-human primate study
Ricin toxin is a plant toxin thought to be a bioterror threat because of its stability and high potency as well as the large worldwide reservoir created as a by-product of castor oil production. As a poison, ricin is so potent that the U.S Centers for Disease Control (CDC) estimates the lethal dose in humans is about the size of a grain of salt. There are currently no effective means to prevent the effects of ricin poisoning. Soligenix, Inc., a clinical stage biopharmaceutical company developing several biodefense vaccines and therapeutics, announced last week promising preliminary results from a preclinical study with its ricin toxin vaccine RiVax, in a non-human primate (NHP) lethal aerosol exposure model.
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U.S. forms an international coalition to fight, defeat ISIS
The United States has announced it is forming a “core coalition” to fight Islamic State in Iraq, and has given the new group of states two weeks to finalize plans to help the Iraqi government and the Kurds in the north intensify the campaign against the militants. The core group consists of NATO members, but it is expected that Iraq’s Sunni neighbors such as Saudi Arabia, Jordan, and the Gulf states (except Jihadists-supporting Qatar), and even Arab countries farther afield such as Egypt and Morocco, will cooperate closely with the coalition and lend support to its operations, and that some of these Sunni countries would join it.
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Growing cyberthreats lead to growing interest in cybersecurity insurance
The increasing sophistication and scope of cyberattacks on businesses – and the increasing damage such attacks are causing – have led to growing interest in cybersecurity insurance. The industry is urging the government to treat cyberattacks as acts of terrorism which should be covered under the Terrorism Risk Insurance Act(TRIA), while also looking into how the Stafford Actcould help companies after a cyberterror attack. At the same time, more private insurers are offering limited cyber-coverage, but many say they would discontinue selling cyber policies if TRIA is not renewed. As the term “cyber-coverage” continues to be defined by large insurers, the insurance product lines continue to change.
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Who is to blame when iCloud is "hacked" – you or Apple?
A hacker’s release of personal photos of actress Jennifer Lawrence and other female celebrities on the Internet on the weekend has again drawn our attention to the security of our personal information online. Apple may wish to absolve itself of responsibility when individuals lose control of their personal data, yet understanding the control of data as a personal matter disregards how iCloud and similar services actually operate. If Apple and other cloud-based services want our trust, then they have to acknowledge the role their products play in perpetuating anxieties of data-out-of-control.
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Captured documents reveal IS’s interest in acquiring bioterror weapons
Terrorist organizations have been trying to acquire or build biological weapons of mass destruction, and now, with the growing threat of the Islamic State (IS), analysts are concerned that the Islamist group may gain access to bio-labs in Syria or Iraq. A laptop belonging to a Tunisian who joined ISIS was recently found in Syria, contained documents about how to build and use biological weapons.
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ISIS beheads second American hostage
ISIS has released a video yesterday which depicted the beheading of Steven Sotloff, an American journalist kept captive by the group. It appears that Sotloff had been killed by the same U.K.-born ISIS militant who beheaded James Foley two weeks ago. U.S. intelligence experts said the video was authentic. The killer warned President Obama to “back off” and end the U.S. bombing campaign against ISIS targets, then warned other governments which might join the “evil” actions of the United States against ISIS. The video shows another kneeling captive, who is described as a British national (the U.K. has identified the hostage as David Cawthorne Haines, an aid worker).
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U.S. opens a second drone base in Niger
The Pentagon has reached an agreement with the government of Niger to open a second U.S. drone base in the landlocked country. The base, in the city of Agadez, will help the U.S. Air Force track Islamist militants who have gained control of remote parts of North and West Africa. U.S. and French troops already operate out of a military base in Niamey, Niger’s capital, where drones are set to conduct reconnaissance flights throughout the region.
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Los Angeles thinking of ways to shore up aging infrastructure
Los Angeles, the second-largest city in the nation by population size, has been dealing with crumbling infrastructure for years now. More than 10 percent of the city’s 7,200 miles of water pipes were built ninety years ago. About 40 percent of the region’s 6,500 miles of roads and highways are graded D or F, requiring so much money to fix them that the city is simply concentrating its maintenance efforts on C-graded roads, since they cost less to fix. Additionally, more than 4,000 of the 10,750 miles of sidewalks seriously need repair, according to city officials.
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U.S. strike kills al-Shabab’s spiritual leader
The U.S. military has attacked the Islamic al-Shabab network in Somalia yesterday (Monday). The Pentagon said the operation targeted the group’s fugitive leader. A senior Somali intelligence official said that a U.S. drone targeted al-Shabab leader Ahmed Abdi Godane as he left a meeting of the group’s top leaders. Godane, also known as Mukhtar Abu Zubeyr, is the group’s spiritual leader who forged an alliance between Somali militants and al-Qaeda. About 100 U.S. Navy SEALs and other Special Operation forces have been operating in different parts of Somalia for more than a year now.
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Former head of Internal Affairs at CBP: Agency suffers from “institutional narcissism”; conducting its affairs beyond “constitutional constraints”
In what may become the most explosive scandal in the history of the U.S. Border Patrol, James F. Tomsheck, former head of Internal Affairs at U.S. Customs and Border Protection (CBP), accused his own agency of protecting its agents from criminal charges, including murder, corruption, and graft. Tomsheck also directly pointed the finger at CBP senior management, including former Commissioner Alan Bersin and Chief David Aguilar. Tomsheck, who served until June of this year as the head of internal affairs for U.S. Customs and Border Protection, characterized his agency as suffering from “institutional narcissism” and maintaining a culture which allowed its agents to act beyond “constitutional constraints”
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Better security for Europe’s mass transportation
When a suspicious individual flees on a bus or by train, things usually get tough for the police. This is because the security systems of the various transportation companies and security services are typically incompatible. The EU project, Secur-ED (Secure Urban Mass Transportation – European Demonstrator), aims to correct this by establishing better collaboration among transportation companies within the same city.
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Scientists improve accuracy, reliability of nuclear tests inspection
The Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) operates the International Monitoring System (IMS) — 279 sensors-equipped facilities around the world which detect four types of physical phenomena that can provide evidence of a nuclear explosion having taken place: seismic waves, radioactive nuclei, underwater sound waves, and infrasonic waves. The evidence from the IMS is not always enough to convince signatories of the CTBT that a nuclear test has taken place. Scientists are trying to improve the accuracy and reliability of the IMS system.
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ISIS threat in Iraq exposes Obama’s failed policy in Syria: Administration insiders
President Barack Obama has been coming under growing criticism over his policy – or, as some critics would argue, lack of policy — toward the Jihadist threat in Iraq and Syria. The criticism is increasingly coming from members of his own administration. They argue that the failure to help the moderate elements among the Syrian rebels not only helped Assad stay in power, but also allowed the Jihadists to cement their power over a large swath of Syria and then move south to control a third of Iraq. The president has recently asked for $500 million to help train moderate Syrian rebels, but even those who supported such a move two years ago say it may be too late.
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More headlines
The long view
Kinetic Operations Bring Authoritarian Violence to Democratic Streets
Foreign interference in democracies has a multifaceted toolkit. In addition to information manipulation, the tactical tools authoritarian actors use to undermine democracy include cyber operations, economic coercion, malign finance, and civil society subversion.
Patriots’ Day: How Far-Right Groups Hijack History and Patriotic Symbols to Advance Their Cause, According to an Expert on Extremism
Extremist groups have attempted to change the meaning of freedom and liberty embedded in Patriots’ Day — a commemoration of the battles of Lexington and Concord – to serve their far-right rhetoric, recruitment, and radicalization. Understanding how patriotic symbols can be exploited offers important insights into how historical narratives may be manipulated, potentially leading to harmful consequences in American society.
Trump Aims to Shut Down State Climate Policies
President Donald Trump has launched an all-out legal attack on states’ authority to set climate change policy. Climate-focused state leaders say his administration has no legal basis to unravel their efforts.
Vaccine Integrity Project Says New FDA Rules on COVID-19 Vaccines Show Lack of Consensus, Clarity
Sidestepping both the FDA’s own Vaccines and Related Biological Products Advisory Committee and the CDC’s Advisory Committee on Immunization Practices (ACIP), two Trump-appointed FDA leaders penned an opinion piece in the New England Journal of Medicine to announce new, more restrictive, COVID-19 vaccine recommendations. Critics say that not seeking broad input into the new policy, which would help FDA to understand its implications, feasibility, and the potential for unintended consequences, amounts to policy by proclamation.
Twenty-One Things That Are True in Los Angeles
To understand the dangers inherent in deploying the California National Guard – over the strenuous objections of the California governor – and active-duty Marines to deal with anti-ICE protesters, we should remind ourselves of a few elementary truths, writes Benjamin Wittes. Among these truths: “Not all lawful exercises of authority are wise, prudent, or smart”; “Not all crimes require a federal response”; “Avoiding tragic and unnecessary confrontations is generally desirable”; and “It is thus unwise, imprudent, and stupid to take actions for performative reasons that one might reasonably anticipate would increase the risks of such confrontations.”
Luigi Mangione and the Making of a ‘Terrorist’
Discretion is crucial to the American tradition of criminal law, Jacob Ware and Ania Zolyniak write, noting that “lawmakers enact broader statutes to empower prosecutors to pursue justice while entrusting that they will stay within the confines of their authority and screen out the inevitable “absurd” cases that may arise.” Discretion is also vital to maintaining the legitimacy of the legal system. In the prosecution’s case against Luigi Mangione, they charge, “That discretion was abused.”