• Better understanding of the 1918 Flu Pandemic aids in better infectious disease response today

    The 1918 Flu Pandemic infected over 500 million people, killing at least fifty million. Now, researchers have analyzed the pandemic in two remote regions of North America, finding that despite their geographical divide, both regions had environmental, nutritional, and economic factors that influenced morbidity during the pandemic. Findings from the research could help improve current health policies.

  • New biodefense centers offer modernized approach, face criticism

    A new facility at Texas A&M University is one of three new biodefense centers created by the U.S. Department of Health and Human Services (HHS) to revolutionize the way fatal viruses are countered in the event of an emergency. The $286-million lab features mobile clean rooms that can be detached and moved to form different production or testing systems as the need arises. Not everyone agrees that the design and capabilities of the new center would offer the best response to biothreats.

  • Debate intensifies over whether or not to destroy last stockpile of smallpox

    The world’s health ministers are scheduled to meet later this month to discuss the fate of the last known stockpiles of smallpox, held under tight security in two labs— one in the United States and the other in Russia. Smallpox has been eradicated for more than three decades, but some U.S. health officials say the remaining stockpiles should be kept for further studies. The smallpox virus is being used to develop drugs and safer vaccines in case the virus returns through terrorism or a lab accident. Member nations of the World Health Organization (WHO) once agreed that the last virus strains known to officials would eventually be destroyed, but a set date was never agreed upon.

  • California bill banning use of antibiotics in livestock withdrawn

    The Centers for Disease Control and Preventionreports that 23,000 people die every year from infections that cannot be cured, often due to overuse of antibiotics which creates drug resistant bugs. Last Wednesday, California Assemblyman Kevin Mullin (D-San Mateo) withdrew proposed legislation which would ban the sale of meat and poultry fed on nontherapeutic antibiotics. He lacked sufficient support from fellow legislators.

  • New technology to detect previously undetectable fecal contamination in water

    Technology capable of sampling water systems to find indicators of fecal matter contamination that are thousandths and even millionths of times smaller than those found by conventional methods is being developed by researchers. The researchers have developed an ultrasensitive detection method that can detect molecules associated with human and animal fecal matter in water systems. These extremely small indicators, he explains, have been traditionally difficult to detect but can signal greater levels of contamination, which can lead to illness and even death.

  • Promising agents breach superbug defenses to fight antibiotic resistance

    In the fight against “superbugs,” scientists have discovered a class of agents that can make some of the most notorious strains vulnerable to the same antibiotics that they once handily shrugged off. Scientists have been developing new agents to combat these enzymes, but the agents so far have fallen short. A new class of agents, called metallopolymers, shows promise.

  • New bug sensor saves crops, people

    For hundreds of years humans have attempted to kill unwanted insects. While some blanket methods have been successful, they can be costly and create environmental problems. A new sensor developed by UC Riverside researchers aims to change that by counting and classifying the insects so that the substance used to eradicate the harmful insects can be applied on a precision targeted level. The inexpensive wireless sensors have 99 percent accuracy, and they are expected to have applications fighting insect-borne diseases, such as malaria, and insects that damage crops.

  • 1918 pandemic flu virus mystery solved

    Just as the world was recovering from the devastation of the First World War, another killer swept across the globe. A deadly flu virus attacked more than one-third of the world’s population, and within months had killed more than fifty million people — three times as many as the war — and had done it more quickly than any other illness in recorded history. Until now, the origin of the 1918 pandemic flu virus and its unusual severity have vexed health experts. A new study not only sheds light on the devastating 1918 pandemic, but could also improve vaccination strategies, and pandemic prevention and preparedness.

  • First large-scale dengue vaccine efficacy study achieves primary clinical goals

    Dengue is a threat to nearly half the world’s population, and is a pressing public health priority in many countries in Asia and Latin America where epidemics occur. Sanofi Pasteur, the vaccines division of Sanofi, yesterday announced that the first of two pivotal Phase III efficacy studies with its dengue vaccine candidate has achieved its primary clinical endpoint. The efficacy study showed a significant reduction of 56 percent of dengue disease cases. The study involved more than 10,000 volunteers from Asia.

  • Birds in and around Chernobyl's exclusion zone adapting to ionizing radiation

    Birds in the exclusion zone around Chernobyl are adapting to — and may even be benefiting from — long-term exposure to radiation, ecologists have found. The study is first evidence that wild animals adapt to ionizing radiation, and the first to show that birds which produce most pheomelanin, a pigment in feathers, have greatest problems coping with radiation exposure.

  • Emergency water treatment guidelines questioned

    During floods and other emergencies, treating water for drinking is a must, but how to do it is up for debate. The Environmental Protection Agency’s (EPA’s) recommendations for treating water after a natural disaster or other emergencies call for more chlorine bleach than is necessary to kill disease-causing pathogens and are often impractical to carry out, a new study has found.

  • Detecting and defeating radiological threats

    Brookhaven National Laboratory’s Radiological Assistance Program (RAP) team works to stay ahead of any radiological threats by using many detection tools that have become increasingly sophisticated and user-friendly. During a deployment, researchers and technicians with backgrounds in various aspects of radiological controls and analysis conduct field monitoring and environmental sampling, assessment, and documentation activities to help decision makers choose appropriate protective actions for the safety of both the public and first responders.

  • Amid controversy, Boston City council debates banning Level 4 Biolab

    Boston has long been seen as “America’s Medical Capital,” but that may soon change if the city passes a measure to ban Level 4 Biolab disease research at Boston University’s National Emerging Infectious Diseases Laboratory – research which includes deadly and untreatable strains that could decimate an exposed urban population in the event of an accident or terrorist activity.

  • Ebola outbreak highlights need for global surveillance strategies

    According to the World Health Organization (WHO), the deadly Ebola virus can cause mortality rates up to 90 percent of those individuals who contract the disease. No cure or vaccine exists for Ebola hemorrhagic fever and public health officials are concerned about further spread of the virus in the region. A comprehensive review was published yesterday examining the current state of knowledge of the deadly Ebola and Marburg virus. The review calls for improved global surveillance strategies to combat the emergence of infectious diseases such as the recent outbreak of Ebola in West Africa that has claimed the lives of 122 people in the countries of Guinea and Liberia.

  • New MRSA superbug discovered in Brazil

    Researchers have identified a new superbug that caused a bloodstream infection in Brazilian patients. The new superbug is part of a class of highly-resistant bacteria known as methicillin-resistant Staphylococcus aureus, or MRSA, which is a major cause of hospital and community-associated infections. The superbug has also acquired high levels of resistance to vancomycin, the most common and least expensive antibiotic used to treat severe MRSA infections worldwide. The most worrisome aspect of the discovery is that genomic analyses indicated that this novel vancomycin-resistant MRSA superbug belongs to a genetic lineage that is commonly found outside hospitals (designated community-associated MRSA).