• Coronavirus Cases: Mathematical Modeling Draws More Accurate Picture

    Mathematical modeling can take what information is reported about the coronavirus, including the clearly underreported numbers of cases, factor in knowns like the density and age distribution of the population in an area, and compute a more realistic picture of the virus’ infection rate, numbers that will enable better prevention and preparation, modelers say. “Actual pandemic preparedness depends on true cases in the population whether or not they have been identified,” says one researcher. “With better numbers we can better assess how long the virus will persist and how bad it will get. Without these numbers, how can health care systems and workers prepare for what is needed?”

  • The Coronavirus Crisis: A Catalyst for Entrepreneurship

    Throughout human history, crises have been pivotal in developing our societies. Pandemics have helped advance health-care systems, wars have fueled technological innovations and the global financial crisis helped advance tech companies like Uber and Airbnb. The present coronavirus pandemic will arguably not be an exception; entrepreneurs can be expected to rise to the challenge. Businesses play a key role both in helping society get through an economic crisis and in creating innovations that shape society after a crisis. So one key question is: how will the ongoing crisis influence future society? While it’s hard to predict the future, we can develop an understanding of what is ahead by analyzing current trends. It’s clear the post-pandemic future will be different. What’s happening during the crisis will have a lasting impact on society. Current signs of entrepreneurial initiative and goodwill give us some cause for optimism. In the words of Stanford economist Paul Romer: “A crisis is a terrible thing to waste.”

  • Quantum Computers Will Break the Internet, but Only If We Let Them

    Tomorrow’s quantum computers are expected to be millions of times faster than the device you’re using right now. Whenever these powerful computers take hold, it will be like going from a Ford Model T to the Starship Enterprise. Hackers may soon be able to expose all digital communications by using advanced quantum computers. A new form of cryptography would stop them, but it needs to be put into place now.

  • Lasers to Detect Weapons-Grade Uranium from Afar

    It’s hard enough to identify nuclear materials when you can directly scan a suspicious suitcase or shipping container. But if you can’t get close? A technique for detecting enriched uranium with lasers could help regulators sniff out illicit nuclear activities from as far as a couple of miles away.

  • Putin’s Long War Against American Science

    A decade of health disinformation promoted by President Vladimir Putin of Russia has sown wide confusion, hurt major institutions and encouraged the spread of deadly illnesses. The Putin regime mandates vaccination at home, but has launched a broad and sophisticated disinformation campaign in an effort to lower vaccine rates in Western countries, with two goals in mind: discredit Western science and medicine, and weaken Western societies by facilitating the re-emergence of diseases such as measles, long thought to have been eradicated. The COPVID-19 epidemic has not escaped the notice of the Kremlin’s disinformation and propaganda specialists. “As the pandemic has swept the globe, it has been accompanied by a dangerous surge of false information,” William Broad writes. “Analysts say that President Vladimir V. Putin of Russia has played a principal role in the spread of false information as part of his wider effort to discredit the West and destroy his enemies from within.”

  • Next potential shortage: Drugs needed to run ventilators

    As hospitals scour the country for scarce ventilators to treat critically ill patients stricken by the new coronavirus, pharmacists are beginning to sound an alarm that could become just as urgent: Drugs that go hand in hand with ventilators are running low even as demand is surging.
    Michael Ganio, of the American Society of Health-System Pharmacists, told Michael Rezendes and Linda A. Johnson of the Associated Press that demand for the drugs at greater New York hospitals has spiked as much as 600 percent over the last month, even though hospitals have stopped using them for elective surgery.
    “These ventilators will be rendered useless without an adequate supply of the medications,” Society CEO Paul Abramowitz said in an April 1 letter to Vice President Mike Pence, who is leading President Donald Trump’s coronavirus task force.
    Nationwide, demand for the drugs surged 73 percent in March, according Dan Kistner, a pharmaceuticals expert at Vizient, Inc., which negotiates drug prices for hospitals throughout the country. Supplies, according to Vizient data, have not kept pace.

  • Bolstering Internet Security

    An innovative protection against website counterfeiting developed by Princeton researchers went live on the internet two months ago, on 19 February, boosting security for hundreds of millions of websites. The rollout was the culmination of over two years of close collaboration between research groups at Princeton and Let’s Encrypt, the world’s largest certificate authority serving 200 million websites.

  • Using Innovation, Technology for Drone Ideation Projectd

    Last fall, students in UAB professor Ramaraju Rudraraju’s software engineering class were tasked with a project to take part in ideation for practical uses of drones in farming environments. Through the project, they created a program to map out a farm and various flight patterns and controls for a drone. 

  • Sandia Stimulates Marketplace Recovery with Free Technology Licenses

    Sandia National Laboratories has announced a new, fast-track licensing program to rapidly deploy technology to a marketplace reeling from the effects of COVID-19. The move is designed to support businesses facing widespread, often technical challenges resulting from the pandemic.

  • The Maths Logic That Could Help Test More People for Coronavirus

    Rapid testing of patients is of great importance during a pandemic. But at a time when there aren’t enough COVID-19 tests or testing has been slow, is there a way to enhance the process? As a mathematician and engineer, I asked myself if there was anything a theoretician could do to help meet the demands of the World Health Organization to test as many patients as possible. Well, there might be a way to test many patients with a few test tubes. Instead of using one test tube to produce a result for one sample, we can use several test tubes to test many more samples – with the help of some logic. The general idea is simple. A sample taken from each of our theoretical patients is distributed to half of the test tubes that we have, in different combinations. If we have ten test tubes, for example, we would distribute the samples from each patient into a different combination of five of them. Any tube that tests negative tells us that all the patients that share that test tube must be negative. Meanwhile, test tubes that test positive could contain samples from a number of positive patients – and an individual patient will test positive only if all their associated test tubes are positive.

  • The U.S. Army Wants Your Ventilator Ideas

    The U.S. Army has opened a design competition for ventilators intended for “short-term, rugged field operation…that will support field hospitals,” service officials announced Thursday. Patrick Tucker writers in Defense One that the winners, as determined by judges with the Army’s xTech Covid-19 program, will get $100,000 to develop a prototype. “Select technologies may receive follow-on contracts for additional production and deployment,” the announcement says. Interested participants can enter via the project website. There will be a virtual pitch session on April 13.

  • Coronavirus Research Done Too Fast Is Testing Publishing Safeguards, Bad Science Is Getting Through

    It has been barely a few weeks since the coronavirus was declared a pandemic. The pace at which the SARS-CoV-2 virus has spread across the globe is jolting, but equally impressive is the speed at which scientists and clinicians have been fighting back.
    Irving Steinberg writes in The Conversation that he is a pharmacotherapy specialist and has consulted on infectious disease treatments for decades. “I am both exhilarated and worried as I watch the unprecedented pace and implementation of medical research currently being done. Speed is, of course, important when a crisis such as COVID-19 is at hand. But speed – in research, the interpretation and the implementation of science – is a risky endeavor,” he writes.
    The faster science is published and implemented, the greater the chances it is unsound. Mix in the panic and stress of the current pandemic and it becomes harder to make sure the right information is communicated and adopted correctly. Finally, governing bodies such as the World Health Organization, politicians and the media act as sources of trustworthy messaging and policy making. Each step – research, interpretation, policy – has safeguards in place to make sure the right information is acquired, interpreted and implemented. But pace and panic are testing these safety measures like never before.

  • Point-of-Care Tests for Respiratory Infections Could Save U.K. Millions, Study Finds

    Comprehensive use of currently available point-of-care tests (POCTs) to diagnose respiratory infections could save England’s National Health Service (NHS) up to £89 million ($110 million US) a year, according to a cost analysis published yesterday in the Journal of Medical Economics. Chris Dall writes in CIDRAP that the savings would result from fewer antibiotics being prescribed for the type of acute respiratory infections (ARIs) that are most likely caused by viruses, fewer return trips to the doctor, and fewer antibiotic-related adverse events (AEs). And the savings could rise significantly if more accurate diagnostic tests were available, the authors of the analysis suggest.

  • In the Rush to Innovate for COVID-19 Drugs, Sound Science Is Still Essential

    Hydroxychloroquine and chloroquine have been at the center of debate in recent weeks over which drugs should be used to treat COVID-19. Neither product has strong evidence to support use for this purpose, and small studies reported to date have either had significant flaws or failed to demonstrate effect. Nonetheless, the president can’t seem to stop pushing them, arguing that patients have nothing to lose. As physicians, bioethicists and drug law experts, we have a responsibility to inject caution here. As public officials and scientists rush to innovate, no one should overlook the critical role of strong regulatory protections in supporting our ability to actually figure out which drugs work against COVID-19. Weakening commitment to science and evidence during this crisis truly would be “a cure worse” than the disease.

  • Why It Is So Hard to Produce What’s Needed to Tackle Coronavirus

    Manufacturers are stepping up to meet the severe shortage of ventilators prompted by the current coronavirus pandemic – and not just companies in the medical industry. Numerous firms from the aerospace and defense sectors, and even Formula One, have offered their services. Peter Ogrodnik writes in The Conversation that in the UK, domestic appliance maker Dyson, defense contractor Babcock and the Ventilator Challenge U.K. consortium (including leading firms such as Airbus and Ford) have all received orders to make thousands of new ventilators to meet the government’s target of an extra 30,000. Rather than simply helping scale up production of existing products, these firms are working with designs that have never before been used or tested in real settings. While all efforts are welcome, there are likely to be some major challenges for manufacturers trying to enter the medical devices sector for the first time. Journalists reported with amazement that the first batch of devices from the Ventilator Challenge UK consortium would include just 30 units. But there are some good reasons why novel ventilators can’t simply be turned out in large amounts with just days’ notice.