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HIV Drug to Be Trialed on Coronavirus Patients to See If It Can Fight COVID-19
Coronavirus patients will be treated with an HIV drug or steroid as part of trial to see if existing medications can beat the deadly infection. Sarah Knapton reports in The Telegraph that researchers from the University of Oxford enrolled the first patient last week, and want hospitals to sign up thousands more people in the coming weeks. The trial – which has been expedited by the chief medical officer, Professor Chris Whitty – would usually have taken around 18 months to organize, but red tape has been removed and researchers have worked round the clock to get the experiment up and running within just nine days.
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There's a New Symptom of Coronavirus, Doctors Say: Sudden Loss of Smell or Taste
A loss of a sense of smell or taste may be a symptom of COVID-19, medical groups representing ear, nose and throat specialists have warned. Ryan W. Miller reports in USA Today that the American Academy of Otolaryngology – Head and Neck Surgery and ENT UK, citing a growing number of cases around the globe, each issued warnings about patients who tested positive for the new coronavirus with the only symptom being a lost or altered sense of smell or taste.
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FDA Updates COVID-19 Testing Guidelines to Allow Self-Swab Tests
The FDA has updated its guidelines for COVID-19 testing procedures to make the process easier and less uncomfortable for patients, as well as to help limit the impact of testing on the supply of personal protective equipment (PPE) used by healthcare workers, including protective masks, face shields, gloves and gowns. Darrell Etherington reports in Techcrunch that the change means that people taking a test will be able to conduct their own swab, which will involve swabbing shallowly in their nose.
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Moderna Could Make Experimental COVID-19 Vaccine Available to Healthcare Workers by Fall
There are some hard limits to the vaccine development process that mean we are not going to see any preventative immune therapies to fight the new coronavirus for at least a year to 18 months. Darrell Etherington reports in Techcrunch, however, that Moderna, which is behind the first potential vaccine to enter human clinical trials in the U.S., provided new info on Monday that indicates it will seek to provide access to the vaccine to a limited group, likely consisting of healthcare workers, by as early as this fall.
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Drug Recommended by Trump May Have Saved One Man in Florida, May Have Killed One Man in Arizona
President Donald Trump last week said he was instructing the FDA to fast-track testing of hydroxychloroquine and a related drug, chloroquine, as treatment for COVID-19. Tamar Lapin reports in the New York Post that Rio Giardinieri, 52, who was being treated at the Memorial Regional Hospital in South Florida for coronavirus and pneumonia, was told by a friend about Trump’s recommendation. He took the drug and all his symptoms disappeared. His doctors believe, however, that the episodes he experienced were not a reaction to the medicine but his body fighting off the virus.
CBS News reports that according to CBS affiliate KPHO, a Phoenix-area man has died and his wife was in critical condition after the couple took chloroquine phosphate, . The additive used to clean fish tanks that is also found in an anti-malaria medication that’s been touted by Trump as a treatment for COVID-19. CBS News notes that at a news conference last week, Trump falsely stated that the FDA had just approved the use of an anti-malaria medication called chloroquine to treat patients infected with coronavirus. Even after the FDA chief clarified that the drug still needs to be tested for that use, Trump overstated the drug’s potential upside in containing the virus.On Friday, Dr. Anthony Fauci, the U.S. top infectious disease expert, called Trump’s assertions about hydroxychloroquine “anecdotal” and said there is no evidence that it is effective for COVID-19 patients. But the next day, Trump was still touting the drug on social media.
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Bolstering Realistic Radiation Training
The Radiation Field Training Simulator (RaFTS) technology provides a first responder training solution that can be used to protect against acts of radiological or nuclear terrorism and to deal with their subsequent aftermath.
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Fusion Researchers Endorse Push for Pilot Power Plant in U.S.
The growing sense of urgency around development of fusion technology for energy production in the United States got another boost this week with the release of a community consensus report by a diverse group of researchers from academia, government labs, and industry. High among its recommendations is development of a pilot fusion power plant, an ambitious goal that would be an important step toward an American fusion energy industry.
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Impact of a Second Dust Bowl Would Be Felt Worldwide
The American Dust Bowl of the 1930s - captured by the novels of John Steinbeck - was an environmental and socio-economic disaster that worsened the Great Depression. The Dust Bowl was an extreme event. But due to climate change, massive crop failures are more likely to happen again in the future. A catastrophic shock to U.S. agriculture would deplete reserves, including those of other countries.
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COVID-19 Treatment Might Already Exist in Old Drugs – We’re Using Pieces of the Coronavirus Itself to Find Them
As a systems biologist who studies how cells are affected by viruses during infections, I’m interested in the question how long will it take to develop drugs to treat COVID-19. Finding points of vulnerability and developing a drug to treat a disease typically takes years. But the new coronavirus isn’t giving the world that kind of time. With most of the world on lockdown and the looming threat of millions of deaths, researchers need to find an effective drug much faster.
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COVID-19: Imperial College Researchers’ Model Likely Influenced Public Health Measures
The latest analysis comes from a team modelling the spread and impact COVID-19 and whose data are informing current U,K, government policy on the pandemic. The findings are published in the 9th report from the WHO Collaborating Centre for Infectious Disease Modelling within the MRC Centre for Global Infectious Disease Analysis, J-IDEA, Imperial College London.
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Making Bioweapons Obsolete
As the threats posed by bioterrorism and naturally occurring infectious disease grow and evolve in the modern era, there is a rising potential for broad negative impacts on human health, economic stability and global security. To protect the United States from these dangers, researchers are taking on the ambitious goal of making bioweapons obsolete.
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Safe, Fast Radionuclide Detection
In the event of a radiological release, such as from an improvised nuclear device, immediately assessing the threat to public safety would be critical. Rapid detection of radioactive materials can save lives, reduce the environmental impact of such an event and save taxpayer dollars. Current hand-held detection methods, however, are unreliable at detecting very low levels of alpha radiation from actinides, such as uranium, due to environmental influences.
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COVID-19 Diagnostic Based on MIT Technology Might Be Tested on Patient Samples Soon
As more COVID-19 cases appear in the United States and around the world, the need for fast, easy-to-use diagnostic tests is becoming ever more pressing. A startup company spun out from MIT is now working on a paper-based test that can deliver results in under half an hour, based on technology developed at MIT’s Institute for Medical Engineering and Science (IMES). A variety of MIT research projects could aid efforts to detect and prevent the spread of coronavirus.
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Oxford Scientists Develop Rapid Testing Technology for COVID-19
Oxford University scientists have developed a rapid testing technology for the novel corona virus SARS-CoV-2 (COVID-19). The new test is much faster and does not need a complicated instrument. Previous viral RNA tests took 1.5 to 2 hours to give a result. The research team has developed a new test, based on a technique which is capable of giving results in just half an hour – over three times faster than the current method.
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Coal Developers Risk $600 Billion As Renewables Outcompete Worldwide
Coal developers risk wasting more than $600 billion because it is already cheaper to generate electricity from new renewables than from new coal plants in all major markets, the financial think tank Carbon Tracker warns in a new report. The report also finds that over 60 percent of global coal power plants are generating electricity at higher cost than it could be produced by building new renewables. By 2030 at the latest it will be cheaper to build new wind or solar capacity than continue operating coal in all markets.
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More headlines
The long view
Are We Ready for a ‘DeepSeek for Bioweapons’?
Anthropic’s Claude 4 is a warning sign: AI that can help build bioweapons is coming, and could be widely available soon. Steven Adler writes that we need to be prepared for the consequences: “like a freely downloadable ‘DeepSeek for bioweapons,’ available across the internet, loadable to the computer of any amateur scientist who wishes to cause mass harm. With Anthropic’s Claude Opus 4 having finally triggered this level of safety risk, the clock is now ticking.”
A Brief History of Federal Funding for Basic Science
Biomedical science in the United States is at a crossroads. For 75 years, the federal government has partnered with academic institutions, fueling discoveries that have transformed medicine and saved lives. Recent moves by the Trump administration — including funding cuts and proposed changes to how research support is allocated — now threaten this legacy.
Bookshelf: Preserving the U.S. Technological Republic
The United States since its founding has always been a technological republic, one whose place in the world has been made possible and advanced by its capacity for innovation. But our present advantage cannot be taken for granted.
Autonomous Weapon Systems: No Human-in-the-Loop Required, and Other Myths Dispelled
“The United States has a strong policy on autonomy in weapon systems that simultaneously enables their development and deployment and ensures they could be used in an effective manner, meaning the systems work as intended, with the same minimal risk of accidents or errors that all weapon systems have,” Michael Horowitz writes.
Ukraine Drone Strikes on Russian Airbase Reveal Any Country Is Vulnerable to the Same Kind of Attack
Air defense systems are built on the assumption that threats come from above and from beyond national borders. But Ukraine’s coordinated drone strike on 1 June on five airbases deep inside Russian territory exposed what happens when states are attacked from below and from within. In low-level airspace, visibility drops, responsibility fragments, and detection tools lose their edge. Drones arrive unannounced, response times lag, coordination breaks.
Shots to the Dome—Why We Can’t Model US Missile Defense on Israel’s “Iron Dome”
Starting an arms race where the costs are stacked against you at a time when debt-to-GDP is approaching an all-time high seems reckless. All in all, the idea behind Golden Dome is still quite undercooked.