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New book details safety, security methods for biosciences sites
Recent mishaps at laboratories which mishandled potentially dangerous biological substances and the transmission of the Ebola virus in a U.S. hospital are symptoms at bioscience facilities that two Sandia National Laboratories researchers think could be prevented by implementing the practices in a new book on biorisk management. The new book, Laboratory Biorisk Management: Biosafety and Biosecurity, is the first full-length manuscript on the detailed implementation of biorisk management.
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Repurposing wasted food would feed the hungry, create jobs
Roughly one third of all global food gets wasted. In the United States, that number is even higher, with nearly 40 percent of all food going to waste, making it one of the most wasteful countries in the world. Researchers have developed a new model for recovering would-be wasted — or surplus — food and repurposing it to feed hungry people, generate revenue, and even create jobs. The model — Food System-Sensitive Methodology (FSSM) — was recently piloted in West Philadelphia. The researchers say that applying FSSM nationally would likely yield about 1.1 billion pounds of recovered wasted food annually.
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EU-funded research: Climate change and food safety
The global fresh produce supply chain must take into account climate change in order to ensure food safety, warn EU-funded researchers. This was the key recommendation of the EU-funded VEG-I-TRADE project, which was launched in 2010 to assess the safety of fresh produce in a rapidly evolving context of climate change and expanding international trade.
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Long-distance travelers may contribute to the spread of antibiotic resistance
Swedish exchange students who studied in India and in central Africa returned from their sojourns with an increased diversity of antibiotic resistance genes in their gut microbiomes. These resistance genes were not particularly abundant in the students prior to their travels, but the increases are nonetheless quite significant. The researchers questioned the conventional wisdom that overuse of antibiotics was entirely responsible for the surge in resistance, despite the fact that overuse is a huge problem.
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New drug protects against nuclear radiation’s deadly effects 24 hours after exposure
The threat of a nuclear incident, with the potential to kill or injure thousands of people, has raised global awareness about the need for medical countermeasures that can prevent radiation-induced bodily damage and keep people alive, even if given a day or more after contact with nuclear radiation. An interdisciplinary research team reports a breakthrough in countering the deadly effects of radiation exposure. A single injection of a regenerative peptide was shown significantly to increase survival in mice when given twenty-four hours after nuclear radiation exposure.
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Mobile phone data help track spread of infectious diseases
Tracking mobile phone data is often associated with privacy issues, but these vast datasets could be the key to understanding how infectious diseases are spread seasonally, according to a new study. Researchers used anonymous mobile phone records for more than fifteen million people to track the spread of rubella in Kenya and were able quantitatively to show for the first time that mobile phone data can predict seasonal disease patterns. Harnessing cellphone data in this way could help policymakers guide and evaluate health interventions like the timing of vaccinations and school closings, the researchers said. The researchers’ methodology also could apply to a number of seasonally transmitted diseases such as the flu and measles.
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Toxic chemical found in fish-eating in birds outside of a Georgia’s Superfund site
Researchers have found that a contaminated mixture called Aroclor 1268 has spread beyond a former chemical plant, now a Superfund site, near Brunswick, Georgia. Aroclor 1268 is composed of a suite of toxic chemical compounds known as polychlorinated biphenyls, or PCBs. The chemical was used to produce insulation materials at the Linden Chemical Plant at the Turtle Estuary near Brunswick until 1994.
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Two major U.S. aquifers contaminated with high levels of natural uranium
Nearly two million people throughout the Great Plains and California live above aquifer sites contaminated with natural uranium which is mobilized by human-contributed nitrate. Data from roughly 275,000 groundwater samples in the High Plains and Central Valley aquifers show that many Americans live less than two-thirds of a mile from wells that often far exceed the uranium guideline set by the Environmental Protection Agency. A new study reports that 78 percent of the uranium-contaminated sites were linked to the presence of nitrate, a common groundwater contaminant that originates mainly from chemical fertilizers and animal waste.
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Pfenex awarded contract valued at up to $143.5 million to develop anthrax vaccine
San Diego, California-based Pfenex Inc. the other day announced it has signed a five year, cost plus fixed fee contract valued at up to $143.5 million with the Biomedical Advanced Research and Development Authority (BARDA) of the Department of Health and Human Services (HHS), for the advanced development of Px563L, a mutant recombinant protective antigen anthrax vaccine. The company says the U.S. government is looking to have a stockpile of seventy-five million doses.
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What if it happened again? What we need to do to prepare for a nuclear event
As we observe the 70th anniversary of the bombings of Hiroshima and Nagasaki, it may seem like the threat from nuclear weapons has receded. But it hasn’t; the threat is actually increasing steadily. This is difficult to face for many people, and this denial also means that we are not very well-prepared for nuclear and radiological events. Any nuclear weapon exchange or major nuclear plant meltdown will immediately lead to a global public health emergency. The Ebola outbreak taught the world that we should have resources in place to handle a major health emergency before it happens. What would a Nuclear Global Health Workforce need to be prepared to manage? For that we can look back at the legacy of the atomic bombings of Hiroshima and Nagasaki, as well as the nuclear accidents like Chernobyl and Fukushima.
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Warming-driven substantial glacier ice loss in Central Asia imperils water supplies
Central Asia is the outstanding case for human dependence on water seasonally delayed by glaciers. Nowhere the question about the glacier state is linked so closely to questions of water availability and, thus, food security. The glaciers in Central Asia, however, experience substantial losses in glacier mass and area. Along the Tien Shan, Central Asia’s largest mountain range, glaciers have lost 27 percent of their mass and 18 percent of their area during the last fifty years. Scientists estimate that almost 3,000 square kilometers of glaciers and an average of 5.4 gigatons of ice per year have been lost since the 1960s, saying that about half of Tien Shan’s glacier volume could be depleted by the 2050s.
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Researchers carefully protect dangerous pathogens – but how secure are all their data?
Ebola, smallpox, anthrax and many others: the most dangerous microorganisms are strictly regulated in the United States. The federal government oversees use of sixty-five so-called select agents with “the potential to pose a severe threat to public, animal or plant health, or to animal or plant products.” There has never been as much research performed with these pathogens —to learn more, find cures, or create vaccines — as in the past decade. The sprawl of high containment laboratories has led to a parallel increase in individuals with access to these agents. As of January 2015, approximately 11,000 individuals were on the list. The deadly infectious agents must be kept safely under lock and key, where they can’t threaten the general population or fall into the wrong hands. But even the most physically secure research lab could be the site of a devastating data security breach. As they stand now, information security guidelines published by science regulators with regard to select agents lack the critical level of detail needed to protect data effectively.
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Agroterrorism a serious risk to Americans, U.S. economy: Experts
The word “terrorism” is typically associated with bomb and bullets, but security experts say that there are other types of terrorism which may bring death and disruption, chief among them is agroterrorism. Agroterrorism is the use of animal or plant pathogens to disrupt a nation’s food supply, or use the food supply to spread deadly disease.In 2004, Tommy Thompson, then secretary of Health and Human Services, said that, “For the life of me, I cannot understand why the terrorists have not attacked our food supply, because it is so easy to do.”
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Toxic blue-green algae a growing threat to nation’s drinking, recreational water
A new report concludes that blooms of toxic cyanobacteria, or blue-green algae, are a poorly monitored and underappreciated risk to recreational and drinking water quality in the United States, and may increasingly pose a global health threat. Several factors are contributing to the concern. Temperatures and carbon dioxide levels have risen, many rivers have been dammed worldwide, and wastewater nutrients or agricultural fertilizers in various situations can cause problems in rivers, lakes, and reservoirs.
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U.K. conducted chemical weapons experiments on “unconsenting participants”
In 1963 the U.K. Ministry of Defense’s Porton Down military science center carried out the first of a series of tests to release zinc cadmium sulphide in the atmosphere over Norwich. It was one of many examples of secret experiments conducted in the name of military research during the 1950s and 1960s, now chronicled for the first time in a new book. The book provides a comprehensive overview of state military scientific research on chemical and biological weapons by Britain, the United States, and Canada since the First World War. Between 1946 and 1976, “Britain was turned into a large-scale open-air laboratory; her people into an army of unconsenting participants,” the author writes.
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More headlines
The long view
What We’ve Learned from Survivors of the Atomic Bombs
Q&A with Dr. Preetha Rajaraman, New Vice Chair for the Radiation Effects Research Foundation in Hiroshima and Nagasaki, Japan.
Combatting the Measles Threat Means Examining the Reasons for Declining Vaccination Rates
Measles was supposedly eradicated in Canada more than a quarter century ago. But today, measles is surging. The cause of this resurgence is declining vaccination rates.
Social Networks Are Not Effective at Mobilizing Vaccination Uptake
The persuasive power of social networks is immense, but not limitless. Vaccine preferences, based on the COVID experience in the United States, proved quite insensitive to persuasion, even through friendship networks.
Vaccine Integrity Project Says New FDA Rules on COVID-19 Vaccines Show Lack of Consensus, Clarity
Sidestepping both the FDA’s own Vaccines and Related Biological Products Advisory Committee and the CDC’s Advisory Committee on Immunization Practices (ACIP), two Trump-appointed FDA leaders penned an opinion piece in the New England Journal of Medicine to announce new, more restrictive, COVID-19 vaccine recommendations. Critics say that not seeking broad input into the new policy, which would help FDA to understand its implications, feasibility, and the potential for unintended consequences, amounts to policy by proclamation.
Are We Ready for a ‘DeepSeek for Bioweapons’?
Anthropic’s Claude 4 is a warning sign: AI that can help build bioweapons is coming, and could be widely available soon. Steven Adler writes that we need to be prepared for the consequences: “like a freely downloadable ‘DeepSeek for bioweapons,’ available across the internet, loadable to the computer of any amateur scientist who wishes to cause mass harm. With Anthropic’s Claude Opus 4 having finally triggered this level of safety risk, the clock is now ticking.”
“Tulsi Gabbard as US Intelligence Chief Would Undermine Efforts Against the Spread of Chemical and Biological Weapons”: Expert
The Senate, along party lines, last week confirmed Tulsi Gabbard as Director of National intelligence. One expert on biological and chemical weapons says that Gabbard’s “longstanding history of parroting Russian propaganda talking points, unfounded claims about Syria’s use of chemical weapons, and conspiracy theories all in efforts to undermine the quality of the community she now leads” make her confirmation a “national security malpractice.”