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HHS to fund development of drug for bioterrorism, antimicrobial-resistant infections
HHS says that a public-private is partnership will advance the development of Carbavance, a new option to treat bioterrorism threats and antibiotic-resistant infections. The two bioterrorism Carbavance will address are melioidosis, also known as Whitmore’s disease, and glanders. Both melioidosis and glanders can become resistant to existing antibiotics. Already, with existing antibiotic treatments, approximately 40 percent of people who become ill from these bacteria die from the illness, and up to 90 percent die if not treated.
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Children living near overhead power lines do not have greater risk of leukemia
Children who live near overhead power lines in early life do not have a greater risk of developing childhood leukemia, researchers find. The study included nearly 16,500 children who were diagnosed with leukemia in Britain between 1962 and 2008. An earlier study using information on childhood leukemia diagnosed between 1962 and 1995 had suggested that there was an elevated risk for children born within 600 meters of overhead power lines. This new study includes children diagnosed up until 2008, and finds that children born after the 1980s do not have an increased risk.
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NSF rapid response research grants to fund study of West Virginia chemical spill
On 9 January 2014, crude 4-methylcyclohexane methanol (MCHM), a chemical primarily used to clean coal, leaked from a storage tank near Charleston, West Virginia, and bled into a river upstream of a water-treatment plant. As a result, about 15 percent of the state’s residents were advised not to drink the water. Better to understand the properties of the chemical that contaminated the drinking water, and the plumbing and water-treatment systems surrounding the area, the National Science Foundation (NSF) has awarded Rapid Response Research (RAPID) grants to research teams at three universities. These grants also will provide STEM learning opportunities for undergraduate and graduate students on the research teams.
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Growing body of evidence connects lead’s deleterious effects to criminal behavior
Violent crimes had reached an all-time high in the United States in the early 1990s, but by the end of the decade, the homicide rate had plummeted by more than 40 percent. Many theories were offered to explain this dramatic decline, but a new explanation is gaining credence: the banning of lead from gasoline and paint in the early 1970s. Babies born post-ban were exposed to far less lead – with its proven contribution to lowering IQ and causing attention problems and antisocial tendencies — and twenty years on, these babies became young adults who committed fewer crimes than their predecessors.
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FDA says voluntary phasing out of antibiotics in livestock is working
A study by the Natural Resources Defense Council(NRDC) says that the U.S. Food and Drug Administration allowed eighteen animal drugs to remain on the market despite the agency’s discovery that the drugs posed a high risk of exposing humans to antibiotic-resistant bacteria through food supply. The NRDC criticizes the FDA’s voluntary guidelines for antibiotic phase-out, but observers note that beginning in 2001, the FDA began reviewing thirty approved antibiotic-based feed additives, and that only a few – fewer than the eighteen claimed by NRDC – are still in use, and they, too, will soon be relabeled and not allowed for use in livestock.
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New biofuel sources does not require farmland
While the debate over using crops for fuel continues, scientists are now reporting a new, fast approach to develop biofuel in a way that does not require removing valuable farmland from the food production chain. Their work examines the fuel-producing potential of Streptomyces, a soil bacterium known for making antibiotics.
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Genes of Gypsies show traces of convergent evolution in response to Black Death
The Black Death once exterminated up to 30-50 percent of Europeans. Researchers have identified immune system genes in Europeans and Gypsies that likely underwent convergent evolution during Europe’s deadly epidemics. Immune system genes evolve under the influence of infectious diseases, but few studies have attempted genome-wide assessments of infection-driven evolution.
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Oregon man infected with the plague leaves ICU
Paul Gaylord, a welder from Prineville in rural Oregon, who in July 2012 contracted bubonic plague from a stray cat, has recovered and can now reflect on his experience. After admission to the hospital, Gaylord lapsed into a coma for twenty-seven days. While in a coma, his hands and legs swelled and turned black. The doctors told him that tests showed he was infected with the bubonic plague, and that his fingers would have to be amputated.
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Senegal climate change-induced flooding reaching crisis proportions: UN
Margareta Wahlstrom, the head of the UN disaster risk, last week warned that climate change-induced flooding had reached crisis proportions in Senegal, with some towns and villages now finding themselves underwater for large parts of the year. Wahlstrom, who was in Senegal for a 3-day visit as part of the UN preparations for a new global disaster risk-reduction strategy, said that mayors of coastal and riverside towns and villages told her their streets were flooded ten months out of twelve.
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Chemical, physical traits of post-nuclear detonation fallout identified
Post-detonation nuclear forensics relies on advanced analytical techniques and an understanding of the physio-chemical processes associated with a nuclear detonation to identify the device type and the source of the nuclear material in the device. Researchers have begun to develop a technique that provides a practical approach for looking into the complex physical and chemical processes that occur during fallout formation following a nuclear detonation.
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Antibiotic “smart bomb” targets specific strains of bacteria
Researchers have developed a de facto antibiotic “smart bomb” that can identify specific strains of bacteria and sever their DNA, eliminating the infection. The technique offers a potential approach to treat infections by multi-drug resistant bacteria.
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The 9 January chemical leak in West Virginia is the latest in a long history of industrial accidents
The chemical spill that affected the water source in nine West Virginia counties in early January is part of a long history of industrial accidents resulting from the concentration of chemical and coal-mining operations in the region. The 9 January spill, which saw coal-cleansing chemical which leaked from Freedom Industries’ storage tank into the Elk River, leaving more than 300,000 residents without access to clean tap water for days, is the latest in a history of pollution which has poisoned groundwater, spewed toxic gas emissions, and caused fires and explosions.
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Federal, state chemical safety agencies increasingly hampered by budget cuts
The budgets of state and federal agencies tasked with responding to the Elk River chemical spill have recently been cut, and these cuts have limited these agencies’ ability to prevent or respond to disasters such as the water crisis in West Virginia. “We do less,” said a CDC financial official, when asked the results of cuts. “What [the CDC director] has often been quoted as saying is that threats are not going down and so it is concerning to not be able to grow with the public health threats.”
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Faster way to spot bacteria-tainted food -- and prevent illness
The regular appearance of food poisoning in the news, including a recent event that led to the recall of more than 33,000 pounds of chicken, drives home the need for better bacterial detection long before meats and produce make it to the dinner table.
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FDA allows use of antibiotics in livestock despite “high risk” to humans
The Center for Disease Control and Prevention (CDC) has recently confirmed the link between antibiotic use on industrial farms and the rise of antibiotic resistance, saying there is “strong scientific evidence of a link between antibiotic use in food animals and antibiotic resistance in humans,” and warns of “potentially catastrophic consequences” if resistance is not slowed. The Food and Drug Administration (FDA), however, has quietly allowed thirty potentially harmful antibiotics, including eighteen rated as “high risk,” to remain on the market as additives in farm animal feed and water. The FDA first recognized the risks from the use of antibiotics in animal feed in 1977, when it proposed to withdraw approvals for animal feed containing penicillin and most tetracyclines. The agency has not followed through on its own findings – and has fought court orders to do so — and today 70 percent of all medically important antibiotics sold in the United States are sold for use in livestock production — not on humans.
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More headlines
The long view
We Ran the C.D.C.: Kennedy Is Endangering Every American’s Health
Nine former leaders of the Centers for Disease Control and Prevention (CDC), who served as directors or acting directors under Republican and Democratic administrations, serving under presidents from Jimmy Carter to Donald Trrump, argue that HHS Secretary Roert F. Kennedy Jr. poses a clear and present danger to the health of Americans. He has placed anti-vaxxers and conspiracy theorists at top HHS positions, and he appears to be guided by a hostility to science and a belief in bizarre, unscientific approaches to public health.