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New understanding of key step in anthrax infection
Scientists advance A new hypothesis concerning a crucial step in the anthrax infection process. The research teams have explored the behavior of the toxins that rapidly overwhelm the body as the often-fatal disease progresses. Their findings suggest a new possible mechanism by which anthrax bacteria deliver the protein molecules that poison victims. Anthrax is easily weaponized; the findings could help lead to a more effective cure.
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Irradiated mosquitoes provide malaria vaccine
A new malaria vaccine is derived from mosquitoes that have been irradiated but not killed. The radiation critically weakens the malaria parasite, Plasmodium falciparum, which is extracted from the insects’ salivary glands and administered intravenously to subjects.
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Rapid response, imaging of injuries aided Boston Marathon bombing victims
According to the Centers for Disease Control and Prevention (CDC), bombing survivors have the highest incidence of injury to soft tissue and musculoskeletal systems with the most extreme injury being traumatic amputation, which is reported in up to 3 percent of cases. The Boston Marathon bombings resulted in three fatalities and 264 casualties, with the most severe injuries involving lower extremities of those located closest to the blasts. Blast injuries within civilian populations are rare in the United States, so when they do occur they challenge the medical community rapidly to respond to concurrent evaluation and treatment of many victims.
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Drones help kill bugs dead
The Florida Keys Mosquito Control District is considering using a drone to spot shallow-water pools where mosquitoes breed along the Keys. The 2.2-pound, 2.5-foot-long drone would use infrared cameras to locate the shallow pools and allow the district rapidly to treat those areas with larvicide.
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Heat waves to become more frequent, severe
Climate change is set to trigger more frequent and severe heat waves in the next thirty years regardless of the amount of carbon dioxide (CO2) we emit into the atmosphere, a new study has shown. In the first half of the twenty-first century, these projections will occur regardless of the amount of CO2 emitted into the atmosphere. After then, the rise in frequency of extreme heat waves becomes dependent on the emission scenario adopted.
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Risks of SARS, MERS spreading greater than thought: scientists
Outbreaks such as the severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome coronavirus (MERS) have afflicted people around the world, yet many people think these trends are on the decline. Quite the opposite is true. Scientists discovered that the genetic diversity of a viral population within a host animal could allow a virus to adapt to certain conditions, which could help it reach a human host.
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U.S. radiation exposure guidelines based on unvalidated assumptions: toxicologist
In the 1950s regulators came to adopt the linear no threshold (LNT) dose-response approach to ionizing radiation exposure, which was later generalized to chemical carcinogen risk assessment. A UMass Amherst toxicologist now offers further evidence to support his earlier assertions that two geneticists deliberately suppressed evidence to prevent the U.S. National Academy of Sciences (NAS) from considering an alternative, threshold model, for which there was experimental support. “This isn’t an academic debate; it’s practical, because all of our rules about chemical and low-level radiation are based on unvalidated assumptions and scientific panel decisions made without sound evidence,” the toxicologist says.
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Remote satellites-based early warning system for cholera epidemics
Researchers have established new techniques – based on remote satellites imagery — for predicting the severity of seasonal cholera epidemics months before they occur and with a greater degree of accuracy than other methods based on remote satellite imaging. The findings of the research may provide the essential lead time to strengthen intervention efforts before the outbreak of cholera in endemic regions.
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The U.S. Food Emergency Response Network (FERN) tries to keep food safe
The U.S. Food Emergency Response Network (FERN) has 172 laboratories, including 39 federal, 113 state, and 17 local labs across the states and Puerto Rico. Randy Layton, FERN director, discussed the agency’s work in a July meeting of the International Association for Food Protection (IAFP).
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Climate change was proximate, not primary, cause of 2012 Great Plains drought: study
From May to July 2012, the Great Plains region of the western United States faced a powerful and unpredicted drought. Following seven months of normal rainfall, the drought was one of the largest deviations from seasonal precipitation rates seen in the region since observations began in 1895. Researches find that the drought fell within the bounds of natural atmospheric variability. The strength of the drought, they suggest, was a consequence of the multiple complex nonlinear systems that make up the climate system and did not critically depend on the existence of a strong external forcing.
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Bacteria in drinking water are essential to keeping it clean
Researchers point the way to more sophisticated and targeted methods of ensuring our drinking water remains safe to drink, while still reducing the need for chemical treatments and identifying potential hazards more quickly.
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Lawmakers, scientists question FBI’s investigation, conclusion in 2001 anthrax attacks
Twelve years after the fall 2001 anthrax attacks, and six years after the 2007 FBI’s determination that Bruce Ivins, a top government anthrax researcher at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), was the perpetrator of the attacks (Ivins died in 2008 of apparent suicide), lawmakers and USAMRIID scientists insist that the FBI’s conclusions are not supported by scientific evidence – indeed, that some basic scientific facts make the Bureau’s conclusions untenable.
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Imported food: Shifting from catching problems at the border to preventing them at the source
The Association of Food and Drug officials (AFDO) has published its guidance document for improving imported food safety. The document, entitled “Issues and Concerns with Imported Foods,” was released ahead of the U.S Food and Drug Administration’s (FDA) release of two rules on the same issue. The FDA aims to shift from a regulatory system that focuses on catching problems at the border and into a prevention system to correct issues before they reach the American border.
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Scientists develop safe method for research on deadly flu viruses
In 2012, scientists around the world agreed to a worldwide, yearlong voluntary moratorium on research into the deadly H5N1 bird flu. The ban came after several scientific teams successfully altered the H5N1 viral genome to enable airborne transmission of the bird flu between ferrets — mammals considered a good research model for humans. The public health concern was that altered H5N1 could escape the lab, infect and spread among humans, producing a global pandemic. There was also concern that terrorists would use the altered H5N1 viral genome in large-scale bioterror attacks. Researchers have now been able to turn molecules in human lung cells into viral scissors that cut H5N1 bird flu and similar bugs into pieces. This dismantling of the viral genome in human lung cells will ensure safe research on deadly strains of influenza.
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In arid regions, irrigation can increase malaria risk for a decade
Malaria risk in arid regions often rises when irrigation is introduced, due to increased amounts of standing water that serve as mosquito breeding sites. Globally, the number of people at risk of contracting malaria due to proximity to irrigation canals and related infrastructure has been estimated at 800 million, which represents about 12 percent of the global malaria burden. New irrigation systems in arid regions benefit farmers but can increase the local malaria risk for more than a decade — which is longer than previously believed — despite intensive and costly use of insecticides, a new University of Michigan-led study in northwest India concludes.
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More headlines
The long view
What We’ve Learned from Survivors of the Atomic Bombs
Q&A with Dr. Preetha Rajaraman, New Vice Chair for the Radiation Effects Research Foundation in Hiroshima and Nagasaki, Japan.
Combatting the Measles Threat Means Examining the Reasons for Declining Vaccination Rates
Measles was supposedly eradicated in Canada more than a quarter century ago. But today, measles is surging. The cause of this resurgence is declining vaccination rates.
Social Networks Are Not Effective at Mobilizing Vaccination Uptake
The persuasive power of social networks is immense, but not limitless. Vaccine preferences, based on the COVID experience in the United States, proved quite insensitive to persuasion, even through friendship networks.
Vaccine Integrity Project Says New FDA Rules on COVID-19 Vaccines Show Lack of Consensus, Clarity
Sidestepping both the FDA’s own Vaccines and Related Biological Products Advisory Committee and the CDC’s Advisory Committee on Immunization Practices (ACIP), two Trump-appointed FDA leaders penned an opinion piece in the New England Journal of Medicine to announce new, more restrictive, COVID-19 vaccine recommendations. Critics say that not seeking broad input into the new policy, which would help FDA to understand its implications, feasibility, and the potential for unintended consequences, amounts to policy by proclamation.
Are We Ready for a ‘DeepSeek for Bioweapons’?
Anthropic’s Claude 4 is a warning sign: AI that can help build bioweapons is coming, and could be widely available soon. Steven Adler writes that we need to be prepared for the consequences: “like a freely downloadable ‘DeepSeek for bioweapons,’ available across the internet, loadable to the computer of any amateur scientist who wishes to cause mass harm. With Anthropic’s Claude Opus 4 having finally triggered this level of safety risk, the clock is now ticking.”
“Tulsi Gabbard as US Intelligence Chief Would Undermine Efforts Against the Spread of Chemical and Biological Weapons”: Expert
The Senate, along party lines, last week confirmed Tulsi Gabbard as Director of National intelligence. One expert on biological and chemical weapons says that Gabbard’s “longstanding history of parroting Russian propaganda talking points, unfounded claims about Syria’s use of chemical weapons, and conspiracy theories all in efforts to undermine the quality of the community she now leads” make her confirmation a “national security malpractice.”