Facing an ultimatum issued Monday by Egypt’s powerful army, President Mohamed Morsi, in a midnight speech, defiantly announced that he would not resign under pressure and, if necessary, protect his presidency with his life. Analysts note that the speech was aimed to rally his Islamic supporters and prepare them for likely violence ahead, rather than placate the protesters or signal his willingness to reconcile with the demands of the military. The military gave Morsi until 17:00 Egypt’s time (10:00 a.m. EST) to meet the protesters’ demands – chief among them Morsi’s own resignation. In response to Morsi’s speech, the Egyptian military announced: “We swear to God that we will sacrifice even our blood for Egypt and its people, to defend them against any terrorist, radical or fool.”

On Monday, following days of anti-government demonstrations, which culminated Sunday with millions of Egyptians filling the streets of Egypt’s major cities, the Egyptian military issued an ultimatum to President Mohammed Morsi: the military gave the president forty-eight hours to respond to the demands of the protesters – chief among them that he resigned from the position of president. If Morsi failed to meet the demands of the protesters, the military said it would offer its own “roadmap for the future” of Egypt. Ten government ministers announced their resignation from the cabinet in sympathy with the protesters. The interior Ministry announced its “complete solidarity” with the military. Morsi’s aides indicated he would not give in to the threat of a military coup.

George Osborne, Chancellor of the Exchequer, will today announce the government’s spending plans for FY 2015-16. The U.K. agencies responsible for fighting terrorism — MI6, MI5, and Government Communications Headquarters (GCHQ) — will see a significant increase in their combined £1.9 billion budget, an indication of the David Cameron government’s concern about the growing terrorism threat the United Kingdom.

Clark County, Nevada, Sheriff Doug Gillespie says DHS needs to make a bigger effort to help local law enforcement work on preventing terrorist attacks, instead of responding to them after the fact. Gillespie used the Boston Marathon bombings as an example of the importance of prevention efforts, noting that the response to the attacks was handled well, but that people were already killed and injured.

Two men from upstate New York were charged Wednesday with a scheme to build an X-ray weapon to kill Muslim enemies of the United States and Israel. They planned the weapon to kill the designated targets with lethal radiation, and some of the targets were to be killed in their sleep. The indictment says the two wanted to build a powerful X-ray device that could be placed in a truck and driven near a target. The driver would park, leave the area, and activate the device, “killing human targets silently and from a distance with lethal doses of radiation.”

The National Security Agency (NSA) and Justice Department on Tuesday offered a trenchant defense of the NSA’s surveillance programs. Gen. Keith Alexander, NSA director and commander of the U.S. Cyber Command, told lawmakers that the programs have helped prevent “potential terrorist events” more than fifty times since 9/11. Officials also offered a point-by-point rebuttal of the criticism of the program by civil libertarians, emphasizing that authorities, when they gather phone records, cannot immediately find out the identity or location of the callers.

The Obama administration has informed Congress a few minutes ago that the U.S. intelligence community has determined that the Assad regime has used chemical weapons on several occasions against both rebel forces and Syrian civilians. The U.S. intelligence community says these attacks, each using small quantities of sarin gas, have killed about 150 Syrians. The president’s deputy national security adviser, Ben Rhodes, told reporters that the president had decided to provide “direct military support” to the opposition. Rhodes said the U.S. military assistance to the rebels would be different in “both scope and scale” from what had been authorized before, which included non-lethal equipment such as night-vision goggles and body armor.

A Xerox copy of a 26-page manual with instructions on how to use man-portable air-defense systems, or MANPADS – also called SA-7 — was found in a building in Timbuktu in North Mali which was used by Al Qaeda in the Islamic Maghreb operatives during the 8-month control – April 2012 to February 2013 — of the area by Islamist militants. The Libyan military under Col. Qaddafi had about 15,000 SA-7s, but after the Qaddafi regime fell in November 2011, NATO forces and Libyan militias loyal to the government gained possession of only 5,000 of them. The rest have disappeared into the arsenals of different militias, and have probably found their way to different terrorist organizations in North Africa and the Middle East.

Life-threatening bacterial infections cause tens of thousands of deaths every year in North America, but current methods of culturing bacteria in the lab can take days to report the specific source of the infection, and even longer to pinpoint the right antibiotic that will clear the infection. Researchers have created an electronic chip that can analyze blood and other clinical samples for infectious bacteria with record-breaking speed.