Fruit bats found to be the source of Marburg virus

Published 22 August 2007

As is the case with Ebola, the Marburg virus casues deadly hemorrhagic fever; scientists now find that common fruit bats carry the virus

Fruit bats that roost in caves appear to be the source of Marburg virus, which causes a deadly hemorrhagic fever related to Ebola virus, researchers say. Tests of 1,100 bats of various species turned up the virus in only one common species of fruit bats, the team at the U.S. Centers for Disease Control and Prevention (CDC), at the Medical Research Institute in Franceville, Gabon, and elsewhere reported. The study, published in the Public Library of Science journal PLoS ONE, suggests that Marburg may be more common than previously thought. “Furthermore, this is the first report of Marburg virus being present in this area of Africa, thus extending the known range of the virus,” the researchers write. “These data imply that more areas are at risk for Marburg hemorrhagic fever outbreaks than previously realized and correspond well with a recently published report in which three species of fruit bats were demonstrated to be likely reservoirs for Ebola virus.” The study suggests that controlling these bats may help reduce the threat. The World Health Organization (WHO) said last week that Uganda had contained an outbreak of Marburg fever among gold miners there after two men became infected and one died. A major outbreak of Marburg occurred among gold miners in the Democratic Republic of Congo between 1998 and 2000, killing 128 of 154 people infected. An outbreak in Uige, Angola, in 2004-5 killed 150 people among 163 cases. Ebola has also infected gorillas.

There is no vaccine or specific treatment for either disease, which cause a severe headache and fever followed by rapid debilitation. Death can follow within eight to nine days. As is the case with Ebola, the Marburg virus kills before it can spread far, and while bats have been suspected as the source, no one had been able to show this. The CDC team has been testing bats across several regions of Africa. They found a common species of fruit bat, Rousettus aegyptiacus, was the only one infected with the virus. “These Marburg virus-positive bats represent the first naturally infected non-primate animals identified,” the researchers write.

-read more in JonatahanS Towner et. al, “Marburg Virus Infection Detected in a Common African Bat,” PLoS ONE 2, no. 8 (22 August 2007)