• Resistance shapes the discovery of new insecticides

    By Margaret C. Hardy

    Recent news around the world has focused on the dangers of antibiotic resistance. – and the CDC estimates over two-million illnesses and 23,000 deaths occurred in 2013 as a result of antibiotic resistance in bacteria and fungus. But what of another type of resistance which can also have a huge impact on the population: that to insecticides? Livestock, for example, are affected by buffalo flies; farmers and customers are familiar with the total devastation caused by fruit flies; malaria mosquitoes and bed bugs are becoming more resistant to existing chemicals. Even our pets are affected: fleas and ticks are continuing their march, leading to a need for newer, often more expensive synthetic chemistries. The price of insecticide resistance — in the form of R&D costs for new compounds — is passed from chemical companies, to farmers, to consumers.

  • W.Va. spill leads lawmakers, industry to look at reforming toxic substances law

    The government was slow to respond to the 9 January 2014 massive chemical spill in West Virginia because the law governing such response, the 1976 Toxic Substances Control Act (TSCA), limits regulatory agencies’ authority to investigate such spills.Under TSCA, the EPA must first prove that a chemical poses an unreasonable risk to health or the environment before it can require the needed testing that would show a potential risk. One observer called this a Catch-22, telling a congressional panel that “This is like requiring a doctor to prove that a patient has cancer before being able to order a biopsy.”

  • Floods caused lead poisoning in U.K. cattle

    Massive floods in England and Wales have forced thousands to evacuate their homes and destroyed railways and roads. Scientists say the U.K. floods of recent years carry yet another danger with them: lead poisoning. Silage cut from fields soon after they were inundated in the 2012 floods and then fed to cattle raised the lead levels in the animals, killing some of them. Blood samples taken from cattle showed that all of them had lead levels beyond the safe limit for human consumption. An autopsy carried out on one of the casualty animals found lead concentrations 79 times the safe level in its kidney. The contaminated material is thought to originate from historical metal mining in the area. Scientists say a number of river catchments throughout England and Wales face a similar risk.

  • North Carolina brain surgery patients exposed to deadly disease

    Officials at a North Carolina hospital last Tuesday notified eighteen patients that they might have been exposed to Creutzfeldt-Jakob disease (CJD), a degenerative brain disease which is always fatal and which makes those infected exhibit symptoms of dementia before they die. The eighteen patients had brain surgery performed on them since 18 January. A patient operated on that that day was subsequently tested positive for the disease. The hospital said that the surgical instruments used on the patient with CJD were sterilized, but were “not subjected to enhanced sterilization procedures.’

  • Real-time livestock disease situational awareness

    Veterinarians are the U.A. first responders for animal health, acting as the primary line of defense against animal disease outbreaks and are essential to the protection of our animal industries and economy. Researchers at the National Center for Foreign Animal and Zoonotic Disease Defense (FAZD Center) are working with veterinarians, federal and state animal health officials, and industry partners to improve real-time situational awareness of animal diseases.

  • Security of dirty bomb materials in U.S. inadequate: experts

    There are more than 5,000 medical and research devices in the United States containing high-activity radiation sources, including 700 with category-1 sources. Category-1 radiation material could be used by terrorists in dirty bombs. The security measures developed by the industry were written with accident prevention in mind, not in order to thwart a deliberate, forcible effort by terrorists or criminals to gain control of the toxic material. In addition, radioactive materials were considered to be “self-protecting,” because it was assumed that the powerful radiation would deter anyone thinking of tampering with these devices. Terrorist bomb-makers, however, showed themselves to be more technologically-savvy than earlier thought, and, in any event, suicide bombers would not be deterred by the risk of radiation poisoning.

  • HHS to fund development of drug for bioterrorism, antimicrobial-resistant infections

    HHS says that a public-private is partnership will advance the development of Carbavance, a new option to treat bioterrorism threats and antibiotic-resistant infections. The two bioterrorism Carbavance will address are melioidosis, also known as Whitmore’s disease, and glanders. Both melioidosis and glanders can become resistant to existing antibiotics. Already, with existing antibiotic treatments, approximately 40 percent of people who become ill from these bacteria die from the illness, and up to 90 percent die if not treated.

  • Children living near overhead power lines do not have greater risk of leukemia

    Children who live near overhead power lines in early life do not have a greater risk of developing childhood leukemia, researchers find. The study included nearly 16,500 children who were diagnosed with leukemia in Britain between 1962 and 2008. An earlier study using information on childhood leukemia diagnosed between 1962 and 1995 had suggested that there was an elevated risk for children born within 600 meters of overhead power lines. This new study includes children diagnosed up until 2008, and finds that children born after the 1980s do not have an increased risk.

  • NSF rapid response research grants to fund study of West Virginia chemical spill

    On 9 January 2014, crude 4-methylcyclohexane methanol (MCHM), a chemical primarily used to clean coal, leaked from a storage tank near Charleston, West Virginia, and bled into a river upstream of a water-treatment plant. As a result, about 15 percent of the state’s residents were advised not to drink the water. Better to understand the properties of the chemical that contaminated the drinking water, and the plumbing and water-treatment systems surrounding the area, the National Science Foundation (NSF) has awarded Rapid Response Research (RAPID) grants to research teams at three universities. These grants also will provide STEM learning opportunities for undergraduate and graduate students on the research teams.

  • Growing body of evidence connects lead’s deleterious effects to criminal behavior

    Violent crimes had reached an all-time high in the United States in the early 1990s, but by the end of the decade, the homicide rate had plummeted by more than 40 percent. Many theories were offered to explain this dramatic decline, but a new explanation is gaining credence: the banning of lead from gasoline and paint in the early 1970s. Babies born post-ban were exposed to far less lead – with its proven contribution to lowering IQ and causing attention problems and antisocial tendencies — and twenty years on, these babies became young adults who committed fewer crimes than their predecessors.

  • Oregon man infected with the plague leaves ICU

    Paul Gaylord, a welder from Prineville in rural Oregon, who in July 2012 contracted bubonic plague from a stray cat, has recovered and can now reflect on his experience. After admission to the hospital, Gaylord lapsed into a coma for twenty-seven days. While in a coma, his hands and legs swelled and turned black. The doctors told him that tests showed he was infected with the bubonic plague, and that his fingers would have to be amputated.

  • Senegal climate change-induced flooding reaching crisis proportions: UN

    Margareta Wahlstrom, the head of the UN disaster risk, last week warned that climate change-induced flooding had reached crisis proportions in Senegal, with some towns and villages now finding themselves underwater for large parts of the year. Wahlstrom, who was in Senegal for a 3-day visit as part of the UN preparations for a new global disaster risk-reduction strategy, said that mayors of coastal and riverside towns and villages told her their streets were flooded ten months out of twelve.

  • Chemical, physical traits of post-nuclear detonation fallout identified

    Post-detonation nuclear forensics relies on advanced analytical techniques and an understanding of the physio-chemical processes associated with a nuclear detonation to identify the device type and the source of the nuclear material in the device. Researchers have begun to develop a technique that provides a practical approach for looking into the complex physical and chemical processes that occur during fallout formation following a nuclear detonation.

  • Antibiotic “smart bomb” targets specific strains of bacteria

    Researchers have developed a de facto antibiotic “smart bomb” that can identify specific strains of bacteria and sever their DNA, eliminating the infection. The technique offers a potential approach to treat infections by multi-drug resistant bacteria.

  • The 9 January chemical leak in West Virginia is the latest in a long history of industrial accidents

    The chemical spill that affected the water source in nine West Virginia counties in early January is part of a long history of industrial accidents resulting from the concentration of chemical and coal-mining operations in the region. The 9 January spill, which saw coal-cleansing chemical which leaked from Freedom Industries’ storage tank into the Elk River, leaving more than 300,000 residents without access to clean tap water for days, is the latest in a history of pollution which has poisoned groundwater, spewed toxic gas emissions, and caused fires and explosions.