PERSPECTIVE: PoisoningHistory of Nerve Agent Assassinations

Published 14 September 2020

Poisoning political opponents or enemies is not new. Reviews of chemical and biological weapons (CBW) usage through the 20th century similarly list successful and attempted assassinations with mineral poisons or animal and plant toxins in and outside of war. Modern chemical weapons (CW) – typically human-made toxic compounds standardized for use on battlefields – have rarely been selected to target individuals – but a spate of recent political poisonings indicate that this may be changing.

On 20 August, the Russian anti-corruption activist Alexei Navalny fell ill during a return flight to Moscow and was hospitalized in the Siberian town of Omsk after an emergency landing. Members of his travelling party immediately suspected poisoning, an impression hospital staff reinforced when they refused Navalny’s personal physician access to his medical records.

Following his airlifting to Berlin for further examination and specialist treatment, the Charité hospital issued a statement on 24 August which preliminary findings indicated exposure to “a substance from the group of cholinesterase inhibitors.” Even though the hospital could then not name the specific poison used, it added that multiple tests by independent laboratories had confirmed the effect of the poison. The hospital was also treating him with the antidote atropine.

J. P. Zabders writes in The Trench that the references to a cholinesterase inhibitor and atropine were the first strong indicators of a neurotoxicant, to which nerve agents like sarin, VX or the novichoks belong.

A week later, on 2 September, German Chancellor Angela Merkel confirmed the assassination attempt with a novichok agent at a press conference. She drew on the conclusions from biomedical analyses by the Institut für Pharmakologie und Toxikologie der Bundeswehr (Bundeswehr Institute of Pharmacology and Toxicology), one of the top laboratories designated by the Organization for the Prohibition of Chemical Weapons to investigate biomedical samples.

He adds:

Poisoning political opponents or enemies is not new. In his almost 600 pages-long Die Gifte in der Weltgeschichte (1920) [The poisons in world history; re-issued 2010] the German pharmacologist Louis Lewin detailed chapter after chapter how besides criminals and spurned lovers, rulers, leaders, undercover agents and conspirators applied the most noxious substances in pursuing domestic political or international geopolitical objectives. Reviews of chemical and biological weapons (CBW) usage through the 20th century similarly list successful and attempted assassinations with mineral poisons or animal and plant toxins in and outside of war.

Modern chemical weapons (CW) – typically human-made toxic compounds standardized for use on battlefields – have rarely been selected to target individuals. Observers and journalists reported first use of nerve agents by Iraq against Iran in 1983, almost five decades after their initial discovery in Nazi Germany. In March 1995 the world learned of Aum Shinrikyo after its members had released the nerve agent sarin in the Tokyo underground. However, during the previous eight months the extremist cult had also resorted to both sarin and VX in attempts to assassinate judges about to rule against Aum Shinrikyo and individuals who posed a threat or had defected from the religious group. These were the first and for more than a decade and a half the only reports of neurotoxicants used to murder individuals.

North Korea’s killing of Kim Jong-nam, half-brother with a binary form of VX in February 2017, and the March 2018 attempt by Kremlin agents to poison former KGB double agent Sergei Skripal in Salisbury, U.K. with a nerve agent “novichok” – and the attempt by Russian government operatives to use novichock to poison Navalny – indicate that battlefield nerve agents are being used more and more by authoritarian regimes to eliminate political opponents.