• Better tools for tracing food-borne illness to source

    Research could make it easier for public health investigators to determine if a case of food poisoning is an isolated incident or part of a larger outbreak. The study focuses on a test called multi-locus variable number tandem repeats variable analysis (MLVA). The test, which is increasingly used in the detection and investigation of foodborne outbreaks, analyzes specific sequences of DNA (called loci) that change rapidly enough over time to distinguish outbreak strains from other circulating strains of the bacteria but not so rapidly that connections could be masked by changes arising during the course of an outbreak.

  • Congress may modify the amount, manner by which Project BioShield procurements are funded

    In 2004, Congress passed the Project BioShield Act to provide the federal government with new authorities related to the development, procurement, and use of medical countermeasures against chemical, biological, radiological, and nuclear (CBRN) terrorism agents. Among other things, the authority allows the government to guarantee a market for CBRN medical countermeasures. Under this provision, the secretary of Health and Human Services (HHS) may obligate funds to purchase countermeasures that still need up to ten more years of development. Since 2004, HHS has obligated approximately $3.309 billion to guarantee a government market for countermeasures against anthrax, smallpox, botulism, radiation, and nerve agents. Another provision established a process through which the HHS secretary may temporarily allow the emergency use of countermeasures which lack Food and Drug Administration (FDA) approval. The 113th Congress may also consider modifying the amount and manner by which it funds Project BioShield procurements.

  • Advancing microbial forensics to respond to global biological outbreaks

    Much as human DNA can be used as evidence in criminal trials, genetic information about microorganisms can be analyzed to identify pathogens or other biological agents in the event of a suspicious disease outbreak. Biological outbreaks can include natural occurrences, accidental, or negligent releases from laboratories, biocrimes aimed at individuals or small groups, or acts of bioterrorism and biowarfare intended to affect large populations. The tools and methods used to investigate such outbreaks belong to an emerging discipline known as microbial forensics, but the field faces substantial scientific and technical challenges, says a new report.

  • Scientists: immediate action required to address superbugs’ threat

    Scientists warn that drug-resistant superbugs demand an immediate, serious response and that the steps required to plan for these pathogens were not properly taken in previous decades. “[A] world without effective antibiotics would be ‘deadly,’ with routine surgery, treatments for cancer and diabetes and organ transplants becoming impossible,” says one scientist. The scientists warn that if action is not taken immediately, the massive health gains made since Alexander Fleming’s discovery of penicillin in 1928 will be lost forever.

  • Canada donates Biosafety Level 3 modular laboratory to Caribbean health authorities

    The Biological Security program of Canada’s Global Partnership Program(GPP) has officially transferred a new biological containment laboratory to the Caribbean Public Health Agency(CARPHA). The Biosafety Level 3 (BSL-3) modular laboratory facility, a first in the Caribbean and located in Port of Spain, Trinidad and Tobago, improves diagnostic capabilities for human and veterinary pathogens with high epidemic potential.

  • Leidos awarded DHS Plum Island biolab contract

    DHS awarded Reston, Virginia-based Leidos a prime contract to support and supplement the Science and Technology (S&T) Agricultural Scientific Program at the Plum Island Animal Disease Center (PIADC). The single-award time and materials (T&M) contract has a one-year base period of performance, four one-year options, and a total contract value of approximately $12 million if all options are exercised. Work will be performed in Orient Point, New York.

  • Scientists urge U.S. to do more to detect, prevent use of bioweapons

    Carefully targeted biological weapons could be as dangerous as nuclear weapons, so the United States should invest more resources in developing technologies to detect them, scientists say. What is especially worrisome is that “The advent of modern molecular genetic technologies is making it increasingly feasible to engineer bioweapons,” says one expert. “It’s making people with even moderate skills able to create threats they couldn’t before.” There is another worry: “A high-tech bioweapon could cost only $1 million to build,” the expert adds. “That’s thousands of times cheaper than going nuclear. Iran’s centrifuges alone cost them billions.”

  • Validating air sampling techniques to fight bioterrorism

    Air and surface sampling techniques currently used by the U.S. government are effective in fighting bioterrorism and potentially saving lives, a new study says. Air sampling has been readily accepted for similar uses such as measuring for particulate matter, but using it to detect bacteria in biological terrorism was a new concept instituted after the 9/11 attacks. This type of sampling is now part of a sophisticated system used by the DHS and the Department of Defense. In order for the system to work more efficiently, however, experts say that the detection cycle, which currently takes between 12-36 hours, would need to produce results in a shorter time frame.

  • Battelle shows smart technology for biodefense and hazard avoidance

    Battelle last week announced production of the next generation chemical and biological hazard sensor system, which the company says operates at a fraction of the cost of current technologies. The technology, known as the Resource Effective BioIdentification System (REBS), is a battery-powered system capable of autonomous use with operating costs of less than $1 per day per unit (the company notes that current system costs that can range from $500 - $3,000 per day) and assay costs of $0.04 per sample (compared to current systems at over $100 per sample).

  • DHS cancels acquisition of BioWatch’s Generation 3 technology

    Owing to concerns about BioWatcheffectiveness and high cost, DHS has canceled plans to install an automated technology meant to speed the 24-hour operations of the program, the nation’s system for detecting a biological attack.ASeptember 2012 GAO report estimated that annual costs to operate the Generation 3 technology would be “about four times more” than the existing BioWatch system.

  • PathSensors introduces portable pathogen identifier system

    Baltimore, Maryland-based PathSensors, Inc. has introduced the portable Zephyr Pathogen Identifier system. The company says it delivers rapid, reliable detection of bacteria, virus, and toxins in powder and liquid samples in minutes. The Zephyr Identifier uses CANARY (Cellular Analysis and Notification of Antigen Risks and Yields) technology, which is licensed from the MIT-Lincoln Laboratory.

  • Amid controversy, Boston City council debates banning Level 4 Biolab

    Boston has long been seen as “America’s Medical Capital,” but that may soon change if the city passes a measure to ban Level 4 Biolab disease research at Boston University’s National Emerging Infectious Diseases Laboratory – research which includes deadly and untreatable strains that could decimate an exposed urban population in the event of an accident or terrorist activity.

  • Pocket-sized anthrax detector aids global agriculture

    Bacillus anthracis, the bacteria that causes anthrax, is commonly found in soils all over the world and can cause serious, and often fatal, illness in both humans and animals. The bacteria can survive in harsh conditions for decades. In humans, exposure to B. anthracis may occur through skin contact, inhalation of spores or eating contaminated meat. A credit-card-sized anthrax detection cartridge developed at Sandia National Laboratories and recently licensed to a small business makes testing safer, easier, faster, and cheaper.

  • Identifying the most likely non-state chem-bio threats

    New research finds that Jihadists pose the most likely chem-bio threat, but other actors also featured as top threats. Jihadist actors occupied seven of the top 10 spots in a qualitative analysis; nine of the top 10 in a quantitative analysis; and half of the top 10 in an elicitation analysis.

  • 2014 edition of updated first responder biodetection technology guide available

    A 2014 update to a detailed product guide listing biodetection technologies and sampling products is now available. The updated digest, Biodetection Technologies for First Responders: 2014, provides a comprehensive compilation of commercially available detection devices and products published to help first responders when purchasing equipment and supplies needed to rapidly assess biological threats.