• Effective screening of airline passengers arriving from areas of infectious disease outbreaks

    New study shows that exit-screening at thirty-six airports would have assessed all air travelers at risk of transporting H1N1 out of Mexico at start of 2009 pandemic. Screening at 99 percent of the world’s international airports could have been forgone with negligible missed opportunities to prevent or delay the spread of disease. Screening at just eight airports worldwide would have led to the assessment of 90 percent of all at-risk air travelers.

  • Controlling contagion by restricting mobility

    In an epidemic or a bioterrorist attack, the response of government officials could range from a drastic restriction of mobility — imposed isolation or total lockdown of a city — to moderate travel restrictions in some areas or simple suggestions that people remain at home. Deciding to institute any measure would require officials to weigh the costs and benefits of action, but at present there is little data to guide them on the question of how disease spreads through transportation networks. A new MIT study shows that in the face of an epidemic, even moderate government-mandated travel restrictions would slow contagion.

  • International partnership tries to preempt next global pandemic

    Researchers from Australia, Singapore, and the United States are joining forces, through a $20 million partnership, to help pre-empt and prepare the world for the next human pandemic.

  • Mass religious gatherings in Middle East increase risk of MERS coronavirus spreading globally

    Researchers say that the life-threatening MERS coronavirus which has emerged in the Middle East could spread faster and wider during two international mass gatherings involving millions of people in the next few months – the umrah pilgrimage and the hajj. The researchers describe the most likely pathways of international spread based upon worldwide patterns of air travel.

  • Potential flu pandemic looms

    In the summer of 1968, a new strain of influenza appeared in Hong Kong. This strain, known as H3N2, spread around the globe and eventually killed an estimated one million people. A new study reveals that there are many strains of H3N2 circulating in birds and pigs that are genetically similar to the 1968 strain and have the potential to generate a pandemic if they leap to humans.

  • New bird flu strain adapting to mammals, humans

    Influenza virus depends on its ability to attach to and commandeer the living cells of its host to replicate and spread efficiently. Avian influenza rarely infects humans, but can sometimes adapt to people, posing a significant risk to human health. A genetic analysis of the avian flu virus responsible for at least nine human deaths in China portrays a virus evolving to adapt to human cells, raising concern about its potential to spark a new global flu pandemic.

  • New, drug-resistant pandemic swine flu may go global

    Health experts in Australia have expressed concerned about the threat of a new type of drug-resistant pandemic flu which is circulating in the population at large. These experts say that the new strain of swine flu has learned how to dodge the antiviral Tamiflu. While it is still rare, it is now spreading outside of hospitals. U.K. health officials, who have already recorded eight cases of the new strain in the United Kingdom, agree with their Australian counterparts that the new virus has the potential to turn global.

  • CDC: Severe flu strain spreading across U.S.

    According to the Center for Disease Control(CDC), thirty states  are reporting high levels of flu-like illnesses. The flu  going around this year is called HN32, and this strain is likely to keep people ill for longer periods than other strains.

  • Conquering cholera in Haiti without vaccinating most people

    The Centers for Disease Control and Prevention has been skeptical about the effectiveness of vaccination against cholera in Haiti; it has instead emphasized cleaning up the water supply and improving sanitation as the best ways to check the spread of the disease; a new study suggests that vaccination would be effective, and that cholera could be contained in Haiti by vaccinating less than half the population

  • Pigs in southern China found to be infected with avian flu

    Researchers report for the first time the seroprevalence of three strains of avian influenza viruses in pigs in southern China, but not the H5N1 avian influenza virus; their research has implications for efforts to protect the public health from pandemics

  • Bugs without borders: epidemics spread as bugs acquire resistance to antibiotic

    Researchers show that the global epidemic of Clostridium difficile 027/NAP1/BI in the early to mid-2000s was caused by the spread of two different but highly related strains of the bacterium rather than one as was previously thought; the spread and persistence of both epidemics were driven by the acquisition of resistance to a frontline antibiotic

  • Predicting, preventing, and controlling pandemics

    About 60 percent of infectious diseases are caused by viruses, bacteria, and other pathogens that make the jump to humans from other species; this includes some of the most devastating disease outbreaks of the past thirty years, including HIV/AIDS, Ebola, and SARS; despite the huge and rising toll of such diseases, many gaps remain in our understanding of how these “zoonoses” evolve, develop, and spread — gaps that must be filled if we are to succeed in preventing or at least reducing the impact of a next pandemic

  • Mathematics offers new weapon in fight against pandemics

    Mathematicians have developed a powerful tool to quantify the spread and infectiousness of viruses like the pandemic H1N1 flu strain, a tool which can be used together with modern laboratory techniques to help the healthcare system plan its response to disease outbreaks

  • Research on enhanced transmissibility in H5N1 influenza: the debate continues

    How can scientists safely conduct avian flu research if the results could potentially threaten, as well as save, millions of lives? Enhancing and analyzing the transmissibility of the H5N1 virus could, on the one hand, provide insights that could help prevent or treat a future outbreak of H5N1, or, on the other hand, it may provide a roadmap for a bad actor deliberately to bring about an influenza pandemic or lead to an inadvertent release of a virus with enhanced transmissibility

  • Non-lethal cures: new antibiotic cures disease by disarming pathogens, not killing them

    A new type of antibiotic can effectively treat an antibiotic-resistant infection by disarming instead of killing the bacteria that cause it; this is good news, since new drugs are badly needed for treating infections with the bacterium Acinetobacter baumannii, a pathogen that most often strikes hospital patients and immune- compromised individuals through open wounds, breathing tubes, or catheters