• Research on enhanced transmissibility in H5N1 influenza: the debate continues

    How can scientists safely conduct avian flu research if the results could potentially threaten, as well as save, millions of lives? Enhancing and analyzing the transmissibility of the H5N1 virus could, on the one hand, provide insights that could help prevent or treat a future outbreak of H5N1, or, on the other hand, it may provide a roadmap for a bad actor deliberately to bring about an influenza pandemic or lead to an inadvertent release of a virus with enhanced transmissibility

  • Non-lethal cures: new antibiotic cures disease by disarming pathogens, not killing them

    A new type of antibiotic can effectively treat an antibiotic-resistant infection by disarming instead of killing the bacteria that cause it; this is good news, since new drugs are badly needed for treating infections with the bacterium Acinetobacter baumannii, a pathogen that most often strikes hospital patients and immune- compromised individuals through open wounds, breathing tubes, or catheters

  • Genetic sleuthing uncovers deadly new virus in Africa

    An isolated outbreak of a deadly disease known as acute hemorrhagic fever, which killed two people and left one gravely ill in the Democratic Republic of Congo in the summer of 2009, was probably caused by a novel virus scientists have never seen before

  • Concerns about next month’s Hajj grow as Saudi Arabia identified as source of Sars-like outbreak

    The U.K. Health Protection Agency and World Health Organization are attempting to identify a new Sars-like virus which has infected two people so far, one who has died and another who is receiving intensive care; the source of the virus appears to be in Saudi Arabia, which raises concerned that the Hajj pilgrimage next month could provide the virus a chance to spread around the world; thousands of Muslims from all over the world attend the event every year

  • U.S. urgently needs better bioterrorism, disease tracking system

    Nearly eleven years have passed since the fall 2001 bioterrorism-related anthrax attacks that shook the United States, killing five people and injuring seventeen, a leading bioterrorism expert says the country has still not learned its lesson; he says that current data mining approaches are passive and do not provide immediate solutions to the emergencies at hand, proposing instead an electronic, clinician-based reporting system which would have the capacity to limit the impact of a bioterrorism attack

  • U.S. schools not ready for next pandemic

    Many U.S. schools are not prepared for bioterrorism attacks, outbreaks of emerging infectious diseases, or pandemics, despite the recent 2009 H1N1 influenza pandemic which resulted in more than 18,000 deaths worldwide

  • New synthesis devised for most useful, yet expensive, antimalarial drug

    In 2010 malaria caused an estimated 665,000 deaths, mostly among African children; now, chemists have developed a new synthesis for the world’s most useful antimalarial drug, artemisinin, giving hope that fully synthetic artemisinin may help reduce the cost of the live-saving drug in the future

  • World-wide alert for Yosemite hantavirus risk

    U.S. health officials have alerted thirty-none countries that their citizens, who, as tourists,  have stayed in Yosemite National Park tent cabins this summer, may have been exposed to a deadly mouse-borne hantavirus

  • Improved disaster resilience is imperative for U.S: report

    A new report from the National Academies says that it is essential for the United States to bolster resilience to natural and human-caused disasters, and that this will require complementary federal policies and locally driven actions that center on a national vision – a culture of resilience; improving resilience should be seen as a long-term process, but it can be coordinated around measurable short-term goals that will allow communities better to prepare and plan for, withstand, recover from, and adapt to adverse events

  • Bad news: avian influenza virus can now infect mammals

    A novel avian influenza virus has acquired the ability to infect aquatic mammals and was responsible for an outbreak of fatal pneumonia that recently struck harbor seals in New England; any outbreak of disease in domestic animals or wildlife, while an immediate threat to wildlife conservation, must also be considered potentially hazardous to humans

  • DARPA demonstrates quick vaccine development for hypothetical pandemic

    A World Health Organization (WHO) estimates that between 20 and 50 percent of the world’s population will be affected if a pandemic were to emerge; WHO forecasts “it may be six to nine months before a vaccine for a pandemic virus strain becomes available”; DARPA reports that rapid fire test of novel, plant-based production method delivers more than ten million doses of H1N1 VLP influenza vaccine candidate in one month

  • Demystifying viruses' copying mechanism allows new vaccines for elusive viruses

    Certain kinds of viruses such as those that cause the common cold, SARS, hepatitis, and encephalitis, copy themselves using a unique mechanism, according to researchers; the discovery sheds light on a previously identified, but never-before-understood region of an enzyme associated with the process of replicating genetic material

  • Measuring the uncertainties of pandemic influenza

    Researchers have highlighted three factors that could ultimately determine whether an outbreak of influenza becomes a serious epidemic that threatens national health; the research suggests that the numbers in current response plans could be out by a factor of two or more depending on the characteristics of the particular pandemic influenza

  • Better tracking of influenza

    Brown University researchers have created a reliable and fast flu-detection test that can be carried in a first-aid kit; the prototype device isolates influenza RNA using a combination of magnetics and microfluidics, then amplifies and detects probes bound to the RNA; the technology could lead to real-time tracking of influenza

  • Improving malaria control and vaccine development

    Each year more than 250 million people worldwide contract malaria, and up to one million people die; malaria is particularly dangerous for children under five and pregnant women; Plasmodium falciparum is the most lethal of the four Plasmodium species, and is responsible for most clinical disease