• T cells offer new promise for vaccines for plague and bacterial pneumonias

    There is currently no licensed plague vaccine in the United States, which is too bad because Yersinia pestis is arguably the most deadly bacteria known to man; most of the plague vaccine candidates that have been studied aim to stimulate B cells to produce plague-fighting antibodies, but animal studies suggest that antibodies may not be enough to protect humans from pneumonic plague; new studies show that T cells can also fight plague — and may be better candidates with which to develop a plague vaccine

  • Dr. Kavita Berger, biosecurity expert

    Project BioShield, launched in 2004 with a $5 billion funding from Congress, aims to encourage the development of vaccines against bioterror agents; the project has divided the scientific community with regard to the direction of R&D effort funded by the project; some scientists in the field argue that the development and stock-piling of vaccines for known diseases, such as polio, plague, botulism, and anthrax, is a waste of funding — funding which could, and should, be used to develop a universal vaccine which would counteract not only known bioterror agents, but yet-unknown agents, also called “designer pathogens”

  • Randall Larsen, executive director of the WMD Commission

    Critics point out that Project BioShield, created in 2003 to address the lack of medical countermeasures to deal with chemical, biological, radiological, or nuclear terrorism agents, is yet to deliver a single vaccine to any of the known bioterror agent; they also point out to the cancellation of a $877.5 million contract with an inexperienced San Francisco company to develop an anthrax vaccine as emblematic of the program; Randall Larsen, executive director of the WMD Commission, argues that “There are always going to be problems when you’re making a new stealth bomber, nuclear powered submarine, or pharmaceutical for biodefense—- “; he also points out that the EPA R&D budget is about half the budget of the Marine Corp. marching band

  • California mandates vaccinations after worst Whooping Cough epidemic in 60 years

    In 2010 California experienced the worst epidemic of whooping cough since 1947; the disease killed ten and infected more than 7,800 people; to avoid another outbreak a new California law requires children in seventh to twelfth grades to be vaccinated against Whooping Cough; the outbreak may have been the result of decreases in vaccinations among children

  • Mosquito-repelling light barriers will reduce spread of malaria

    Malaria accounts for 20 percent of all childhood deaths in Africa; a Columbia University experimental physicist is developing a “light shield” consisting of light barriers that can repel mosquitoes by throwing off the insects’ ability to navigate and detect humans via light and heat

  • GAO: HHS does not have plan for IT pandemic surveillance

    The Health and Human Services (HHS) Department has not developed a strategic plan for a national electronic network for public health situational awareness four years after being told to do so by Congress, according to the GAO

  • Virulent Haitian cholera strain to dominate the Americas

    The high death rate of the Haiti cholera relative to earlier outbreaks in the region (for example, Peru 1991) could partly be because medical care, nutrition, and HIV levels are worse in earthquake- and poverty-stricken Haiti than Peru — but it could also be due to a nastier cholera toxin

  • New Jersey lab on the forefront of fighting bioterrorism

    A New Jersey company is working on defense against biological warfare; the 3-year $8.2 million contract with the Department of Defense calls for it to develop drug molecules used to combat biological warfare pathogens — centering its research around eight bacterial pathogens (although for security reasons, the list of pathogens has not been made public)

  • Capitalism to strengthen U.S. response capability to epidemics, bioterrorism

    The H1N1 flu pandemic highlighted critical gaps in the response capability of the United States, among them: the United States relies almost entirely on foreign suppliers for influenza vaccines and, perhaps as important, production of vaccines for a novel disease strain can take as long as six months; the U.S. Department of Health and Human Services (HHS) wants to reinvent the U.S. medical countermeasures enterprise, from new doctrines for regulatory approvals to nimble, domestic manufacturing capability developed in partnership with the private sector

  • Senate passes sweeping food safety bill

    The Senate passed legislation Tuesday to make food safer in the wake of deadly E. coli and salmonella outbreaks, potentially giving the government broad new powers to increase inspections of food processing facilities and force companies to recall tainted food; the $1.4 billion bill, which would also place stricter standards on imported foods, passed the Senate 73-25

  • MS drug to lead fight against bioterrorism

    A drug already approved for treating multiple sclerosis show promise as a long sought treatment for victims of bioterrorist attack with botulinum neurotoxin — which is 10,000 times deadlier than cyanide and the most poisonous substance known to man

  • Bandages changes color to indicate state of a wound

    Medical dressings are effective at protecting the site of an injury, but to examine a wound they must be removed; this can not only be painful for a patient, but it can also allow germs to enter the wound and cause infection; researchers developed dressing materials and plasters that do not need to be removed to check the state of a wound — they indicate pathological changes in the skin by changing from yellow to purple

  • Detecting use of abnormal organisms as bioterror weapons

    Organisms have the potential to cause disease, but they can be altered to cause an unrecognized diseases or a process a process that doctors have not associated with that organism; this makes altered forms of bacteria like salmonella or E. coli the potential “bombs” in a bio-terrorist attack, but scientists at Purdue University developed a new way to look at those bacteria; now, West Virginia University is testing its potential

  • U.S. shifts bio-defense R&D approach to "platform technologies"

    The Obama administration’s new $5.9 billion bio-defense plan features a strategy to fund so-called “platform technologies” that apply to many different infectious disease threats, whether they be bioterrorism (anthrax), pandemics (influenza), or infectious diseases affecting the developing world (malaria); this money could provide an extra incentive to justify corporate R&D investments in vaccine, drug, and diagnostic technologies

  • Concerns over bioterrorism grow

    Recent concern about the growing threat of bioterrorism attacks that could strike cities throughout the world has led governments, militaries, and the biopharmaceutical industry to a heightened state of alert; in response to this threat, the United States is accelerating preparing institutions and procedures for the potential danger